ELDR
ELDR is a lncRNA demonstrating correlated expression at E14.5 and in the adult brain.[1]
Contents
Annotated Information
Name
Approved symbol:ELDR
Approved name:EGFR long non-coding downstream RNA
HGNC ID:49511
Previous name:long intergenic non-protein coding RNA 1156
Previous symbol:LINC01156
Alias symbol:Fabl
RefSeq ID:NR_110426
Characteristics
Among those lncRNA loci with detectable β-gal signal in the adult brain, β-gal activity was detected at E14.5 for the ELDR loci.[1]
Expression
In the adult brain, ELDR+ cells are found scattered throughout the neocortex in a pattern resembling that of cortical interneurons, which are developmentally generated in the VTel[1]
Diseases
Please input information here.
Labs working on this lncRNA
- Departments of Stem Cell and Regenerative Biology and Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138;[1]
- Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139;[1]
- The Broad Institute of MIT and Harvard, Cambridge, MA, 02142;[1]
- Department of Systems Biology, Harvard Medical School, Boston, MA, 02115;[1]
- Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, 02215;[1]
- Institute of Molecular Health Sciences, Swiss Federal Institute of Technology in Zurich, 8093 Zurich, Switzerland[1]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Goff LA, Groff AF, Sauvageau M, Trayes-Gibson Z, Sanchez-Gomez DB, Morse M, Martin RD, Elcavage LE, Liapis SC, Gonzalez-Celeiro M, Plana O, Li E, Gerhardinger C, Tomassy GS, Arlotta P, Rinn JL. Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain. Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):6855-62. doi: 10.1073/pnas.1411263112. PMID: 26034286; PMCID: PMC4460505.
