HCG11
Contents
Annotated Information
Approved Symbol
HCG11 (HLA complex group 11 (non-protein coding))
Synonyms
"bK14H9.3, FLJ14049, FLJ30357"
lncRNA HCG11 was downregulated in prostate cancer. [1]
GO and KEGG pathway analysis of HCG11. [1]
Chromosome
6p22.2
RefSeq ID
NR_026790
Disease
prostate cancer
Expression
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| qPCR | 5′-AGGAGTGGTTGCATTTGGGA-3′ | 5′-CCCACCACGCAGTGAATAGT-3′[1] |
HCG11 is significantly higher in ovary,breast,thyroid and prostate. TCGA analysis reveals that the expression of HCG11 is significantly suppressed in prostate cancers compared with adjacent normal tissues [1]
Function
Downregulation of HCG11 predicts a poor prognosis in prostate cancer. [1] HCG11 has the ability in the regulation of signal transduction, transcription, cell adhesion, and development.[1]
Labs working on this lncRNA
- State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai, 200433, People's Republic of China.[1]
- Center of Translational Medicine, Central Hospital of Zibo, Zibo, 255036, People's Republic of China.[1]
- Center of Translational Medicine, Central Hospital of Zibo, Zibo, 255036, People's Republic of China. [1]
- State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai, 200433, People's Republic of China.[1]
