LINC00152

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Annotated Information

Approved Symbol

LINC00152:long intergenic non-protein coding RNA 152

Previous Symbols

C2orf59, NCRNA00152

Synonyms

MGC4677

Chromosome

2p11.2

RefSeq ID

XR_042051

OMIM ID

_

Ensembl ID

ENSG00000222041

Function

Linc00152 knockdown could inhibit cell proliferation and colony formation, promote cell cycle arrest at G1 phase, trigger late apoptosis, reduce the epithelial to mesenchymal transition (EMT) program, and suppress cell migration and invasion. [1]

Disease

labs working on this lncRNA

  • Department of Infectious Diseases ; Huashan Hospital; Shanghai Medical College; Fudan University ; Shanghai , China.[1]
  • Department of Biochemistry and Molecular Biology, Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, 315211, China.[2]

References

  1. 1.0 1.1 1.2 Zhao J, Liu Y, Zhang W, Zhou Z, Wu J, Cui P, et al. Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer[J]. Cell cycle. 2015,14(19):3112-23.
  2. 2.0 2.1 Pang Q, Ge J, Shao Y, Sun W, Song H, Xia T, et al. Increased expression of long intergenic non-coding RNA LINC00152 in gastric cancer and its clinical significance[J]. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014,35(6):5441-7.

Sequence

>gi|169163205|ref|XR_042051.1| PREDICTED: Homo sapiens misc_RNA (C2orf59), miscRNA

000001 ATGACAGACA CCGAAAATCA CGACTCAGCC CCCTCCAGCA CCTCTACCTG TTGCCCGCCG ATCACAGCCG GAATGCAGCT 000080
000081 GAAAGATTCC CTGGGGCCTG GTTCCAACCG CCCACTGTGG ACTCTGAGGC CTCTGCATTT GCGGGTGGTC TGCCTGTGAT 000160
000161 ATTTTGGTCA TGGGCTGGTC TGGTCGGTTT CCCATTTGTC TGGCCAGTCT CTATGTGTCT TAATCCCTTG TCCTTCATTA 000240
000241 AAAGCAAAAC TAAAGAAAA