MESTIT1
Contents
Annotated Information
Approved Symbol
MESTIT1 （MEST intronic transcript 1, antisense RNA）
Synonyms
NCRNA00040, MEST-AS1
Chromosome
7q32.2
RefSeq ID
NR_004382
OMIM ID
607794
Ensembl ID
ENSG00000272701
Characteristics
MESTIT1 is transcribed from the paternal allele only in the opposite direction to the MEST gene.[1] MESTIT1 is expressed mainly as a 4.2 kb transcript and is only characterized in humans.[1]
Function
MESTIT1 is involved in the regulation of MEST expression during development.[1]
Expression
MESTIT1 is widely expressed at low levels in an opposite orientation to MEST and imprinted (paternally expressed) in all fetal tissues examined.[1]
Labs working on this lncRNA
- Department of Genetics, The Hospital for Sick Children, and Department of Molecular and Medical Genetics, University of Toronto, Toronto, ON, Canada.
References
- ↑ 1.0 1.1 1.2 1.3 1: Nakabayashi K, Bentley L, Hitchins MP, Mitsuya K, Meguro M, Minagawa S, Bamforth JS, Stanier P, Preece M, Weksberg R, Oshimura M, Moore GE, Scherer SW. Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32. Hum Mol Genet. 2002 Jul 15;11(15):1743-56.
Sequence
>gi|161087002|ref|NR_004382.1| Homo sapiens MEST intronic transcript 1, antisense RNA (MESTIT1), long non-coding RNA
000001 TTAAAAGGCA TCCCTTACGC CTTTGAAAAG TGTAGAGTAT CACGAAGTGT CTGTGTTCAT TTTCTGACCG TAAACTGAAA 000080
000081 TACTGGTGAA CAAACGTGGG GTGCGAGCGG GTGAGCGGGG CGGCCGGCCG GTGCCCGCTG CATCCAGAGG GGGCGCTGCA 000160
000161 GGCCTCCCTT CGGCTGCGCA CGGCCCGGGC CCTCCGCGGC TCTGCAACTC TGCACCCCGA AAGGTTCGGT GCTGGACCGC 000240
000241 GGGGCATCCA ACCCGGGACC GGGGGCGACC CACGGACACT GAGGAAACTA CCGCCTATAA GCCTATCATC AGAACCTCTG 000320
000321 GCACAACACA GGCCAGAAAC ACCAGCATCC AAGATGAAGG CAATTTTCTG TTTATGGACT GAGTACCCCA CAAAAGATCT 000400
000401 TATTCTGAAG GCCATGGAAC ATGTCTACCC ACATGGATCA AGTGGGCAGA CTGGAGGAGA AACAGTTTAA AGGCCCTGGG 000480
000481 GGAAGGAGGG AGCGCCAGGG AGAGCTCCTG AAGACAACAG GAATTCCAAG TCTGGCACTC GGGAGAAATC CTCCCTTCAG 000560
000561 ACATTATTGA TGTCTGGCCG AGGAGTTAGG AAAAACTTCC TTGAAGGAGG GATTGAGGTT GAGATGGGCA TGGAACCCAG 000640
000641 ATCTTAGGCA GAGAAAGCAT ATTCCTGTTT GGAAGAACCC TGAGTACAGA AGTCAGCTCA AAGATATCAG CTTGGCCCAA 000720
000721 CCAGGAATTC GCTGTGGGAA GTCTAAGAGA GAAAATGCTG GCCATAATCC CCCAGGAGCC AAAGAGTTAA CGAATCTTCT 000800
000801 AAATGTGCCT GATTTACTTC CAGAAAGGAG CTTCCTCCGC AGGGGGAGAA TTTGACCCAA GGTATAAAAC ACTTGGAGCC 000880
000881 CTGAGAAAAC ACACAGCCAC ACATAAATTC AAAGTCGGCT CTGGCTTGCT CGAAGTTGCA CCCTTTCAGT TCCTCTGGAC 000960
000961 AGATGCTATC CTGGACTGTG CAGGATATCT CATGCAGTAG TACTCCCTCA GCCAGTGGCT TATCACACAT TCTTGTCACA 001040
001041 TTCCAAGTCT AACACAGTTC CGCCTCATGA TAAGACCTCA GATCTGTGCA AAAATTCATG TAGAAAGCTC TGCATTTATT 001120
001121 ATCTCGCTGA TTCACAACAG TGGTATGGGA TCAGCAGAGA TGGTACCACA GATTCAAGAA CCATATTTTT CTAACCCCAG 001200
001201 TTTGAGACCC ATAATATGAC AAGTGCAGGA TATTTATGGA GACAACAAGA CACAACCGGG ACTGCCACTT TCAAGAGCCA 001280
001281 TCATTGTAGA TTCAAATCAA CTAAAACACT TCATAATGGG AGAAACTTGG TTGAACAGGA GCACATGTTA ACGAAGGGGT 001360
001361 TTTGGTTGAG AAACTTACTG AATCAGTAAG ACAGGACCCT TAAAAAGGCT ACTGTGACTG CAGACTGAGG GGAAGTACCA 001440
001441 AAAATAAGCT AATCCTACTC TATTATGCTG GTTAGAACTC ACAGAAAGCA TTTTATTCTG TTCTACAGAG CAGATACATA 001520
001521 TTGAAACAGA GACAAATAGG AATGTGTTCA GAGAAGGTCA ACTAAATGAA TTGCAAACTG AAGGTGTAAC AGTTCTCGTA 001600
001601 TTTTAAGCTC CTACCATGAG CATGGATCTT CACCCAACAT ATCCCTGATC CTCACAGTAG CCTGGCTAGA TGAGTATTTT 001680
001681 CACTCACAGA TTTCAGAGAG AGATACGGCA GCTCGGAACG CTAAGTGTTA GGATGTGAAG GGGCTGGGAA CTGAACGCAG 001760
001761 ATGTGCCTGG CTCCAAAGTT GGCCTTCTTT CCACTACTCC ACACTGCCTC CCTGTTTGAA ATAGATGGGC ATGTTTGGTT 001840
001841 TGAAGAAAAG AAGCCTTGTG GAGTAAGTAG AAGAAGGAAA TGTGTTAGCA GTCCTCAAAT ATTTGTGGAA GCAGCATTAG 001920
001921 ACATTTTATT CTGTATGGCT CCAATGAGTG CAAATTGTAG AGAAACAGAT GTCGATTCAA CATAAAGAAT TTTCCAACAT 002000
002001 AGGGGCTGTC TAGAGGGATT GGGTGGCTCA GCCATTTTGG TATGGGACAA ATTCTCTGTC CACTGGGGGC TGGGTAACCC 002080
002081 TGTGGCAGGT ATGCGAGCTC TGCATGTAAG ACAATGAATG ACCTGCAAGG TCTTTTCCCA TCTGATGTAA AATAAGGCTC 002160
002161 CAAGATGAAC TGGAACTTGG CCAGGGTGAT CCTCTACTGA GGGGACAAAT TCACAGCTCA GTCTTCCCTA GTTATGTCCC 002240
002241 TCAGCCCAGA ACCCTTGGTA CAACATGCTG CTTTGTACTG AGGGCAAGGC AAATTGAAGA CATTATCATC AATAAAATCA 002320
002321 CATCGAGCCC GCTCTCAACC AAATTAACCA ATGTGGCCGG GCGCAGTGGC TCATGCCTGT AATCCCAGCA CTTTGAGGCT 002400
002401 GAAGCAGGCG GATCACTTCA GGTCAGGAGT TCGAGACCAG CCTGGCCAAC ATGGTGAAAC CCCGTCTCTA CCAAAAATAC 002480
002481 AAAAATTAGC CATGTGTAGT GGTGTGTGCC TGTAGTCCCA GCTACTTGGG AGGCTGAGGC AGGAGAATAG CTTGAGTCCC 002560
002561 GGAGGCAGAA GTTGCAGTGA GATGAGATGG CGTCACTGCA CTCCAGCCTG GGTGACAGAG CGAGACTTCA TCTCAAAAAC 002640
002641 AAAACCAAAC AAAAACAAAT TAACCAATAT ATCCCTGAAG CTACTGGTGT GTTCCTCTTC AGGCCCATTT TTGAGTAAAA 002720
002721 GTGTTTGGCT GTAAAAAGCT CAAAAGATGA GTGGCAGACG AGGGAAGCAG TGGAACTGAA TAATCTCTTA CCCAAATAAG 002800
002801 ATGAACCTAA ATGACAGATG GTTGTTTCTC CAGGTGACAG TATTAGTGGG CACCCCTAAA CTATCTTCAC ACACCCTCTG 002880
002881 CATTACTCCA CACATCCCAT TATCCCACAG CTGGTACTTC TTCACCAGGT ACTCCTGCCC CACTATCCCA CACCTAGAGG 002960
002961 ACATTTTATC CACTCAAACA GATAAATAGG CTGAAGGATT CTAATTAAGT AATAGAATCT TGCATTTTTA TAGCTCTTTA 003040
003041 CCCTTTCACA TATATCATCT CATTTGTCAC TCACCACAGT CCCCTAAGGA AAACAGCTAC TTTCTTTCAG ACAGGCAATT 003120
003121 TTCTAGCTGC CTGGGAGCTA GGAGGAGGAA AGGGCTTCAG CACAGGCACA GTCGCTCTTT CTCGCTTTTT TTTTTTTTTC 003200
003201 CTGTTACTAC CTTCCCACAT TAGATTATGC CTCCAGCCAG AA
000081 TACTGGTGAA CAAACGTGGG GTGCGAGCGG GTGAGCGGGG CGGCCGGCCG GTGCCCGCTG CATCCAGAGG GGGCGCTGCA 000160
000161 GGCCTCCCTT CGGCTGCGCA CGGCCCGGGC CCTCCGCGGC TCTGCAACTC TGCACCCCGA AAGGTTCGGT GCTGGACCGC 000240
000241 GGGGCATCCA ACCCGGGACC GGGGGCGACC CACGGACACT GAGGAAACTA CCGCCTATAA GCCTATCATC AGAACCTCTG 000320
000321 GCACAACACA GGCCAGAAAC ACCAGCATCC AAGATGAAGG CAATTTTCTG TTTATGGACT GAGTACCCCA CAAAAGATCT 000400
000401 TATTCTGAAG GCCATGGAAC ATGTCTACCC ACATGGATCA AGTGGGCAGA CTGGAGGAGA AACAGTTTAA AGGCCCTGGG 000480
000481 GGAAGGAGGG AGCGCCAGGG AGAGCTCCTG AAGACAACAG GAATTCCAAG TCTGGCACTC GGGAGAAATC CTCCCTTCAG 000560
000561 ACATTATTGA TGTCTGGCCG AGGAGTTAGG AAAAACTTCC TTGAAGGAGG GATTGAGGTT GAGATGGGCA TGGAACCCAG 000640
000641 ATCTTAGGCA GAGAAAGCAT ATTCCTGTTT GGAAGAACCC TGAGTACAGA AGTCAGCTCA AAGATATCAG CTTGGCCCAA 000720
000721 CCAGGAATTC GCTGTGGGAA GTCTAAGAGA GAAAATGCTG GCCATAATCC CCCAGGAGCC AAAGAGTTAA CGAATCTTCT 000800
000801 AAATGTGCCT GATTTACTTC CAGAAAGGAG CTTCCTCCGC AGGGGGAGAA TTTGACCCAA GGTATAAAAC ACTTGGAGCC 000880
000881 CTGAGAAAAC ACACAGCCAC ACATAAATTC AAAGTCGGCT CTGGCTTGCT CGAAGTTGCA CCCTTTCAGT TCCTCTGGAC 000960
000961 AGATGCTATC CTGGACTGTG CAGGATATCT CATGCAGTAG TACTCCCTCA GCCAGTGGCT TATCACACAT TCTTGTCACA 001040
001041 TTCCAAGTCT AACACAGTTC CGCCTCATGA TAAGACCTCA GATCTGTGCA AAAATTCATG TAGAAAGCTC TGCATTTATT 001120
001121 ATCTCGCTGA TTCACAACAG TGGTATGGGA TCAGCAGAGA TGGTACCACA GATTCAAGAA CCATATTTTT CTAACCCCAG 001200
001201 TTTGAGACCC ATAATATGAC AAGTGCAGGA TATTTATGGA GACAACAAGA CACAACCGGG ACTGCCACTT TCAAGAGCCA 001280
001281 TCATTGTAGA TTCAAATCAA CTAAAACACT TCATAATGGG AGAAACTTGG TTGAACAGGA GCACATGTTA ACGAAGGGGT 001360
001361 TTTGGTTGAG AAACTTACTG AATCAGTAAG ACAGGACCCT TAAAAAGGCT ACTGTGACTG CAGACTGAGG GGAAGTACCA 001440
001441 AAAATAAGCT AATCCTACTC TATTATGCTG GTTAGAACTC ACAGAAAGCA TTTTATTCTG TTCTACAGAG CAGATACATA 001520
001521 TTGAAACAGA GACAAATAGG AATGTGTTCA GAGAAGGTCA ACTAAATGAA TTGCAAACTG AAGGTGTAAC AGTTCTCGTA 001600
001601 TTTTAAGCTC CTACCATGAG CATGGATCTT CACCCAACAT ATCCCTGATC CTCACAGTAG CCTGGCTAGA TGAGTATTTT 001680
001681 CACTCACAGA TTTCAGAGAG AGATACGGCA GCTCGGAACG CTAAGTGTTA GGATGTGAAG GGGCTGGGAA CTGAACGCAG 001760
001761 ATGTGCCTGG CTCCAAAGTT GGCCTTCTTT CCACTACTCC ACACTGCCTC CCTGTTTGAA ATAGATGGGC ATGTTTGGTT 001840
001841 TGAAGAAAAG AAGCCTTGTG GAGTAAGTAG AAGAAGGAAA TGTGTTAGCA GTCCTCAAAT ATTTGTGGAA GCAGCATTAG 001920
001921 ACATTTTATT CTGTATGGCT CCAATGAGTG CAAATTGTAG AGAAACAGAT GTCGATTCAA CATAAAGAAT TTTCCAACAT 002000
002001 AGGGGCTGTC TAGAGGGATT GGGTGGCTCA GCCATTTTGG TATGGGACAA ATTCTCTGTC CACTGGGGGC TGGGTAACCC 002080
002081 TGTGGCAGGT ATGCGAGCTC TGCATGTAAG ACAATGAATG ACCTGCAAGG TCTTTTCCCA TCTGATGTAA AATAAGGCTC 002160
002161 CAAGATGAAC TGGAACTTGG CCAGGGTGAT CCTCTACTGA GGGGACAAAT TCACAGCTCA GTCTTCCCTA GTTATGTCCC 002240
002241 TCAGCCCAGA ACCCTTGGTA CAACATGCTG CTTTGTACTG AGGGCAAGGC AAATTGAAGA CATTATCATC AATAAAATCA 002320
002321 CATCGAGCCC GCTCTCAACC AAATTAACCA ATGTGGCCGG GCGCAGTGGC TCATGCCTGT AATCCCAGCA CTTTGAGGCT 002400
002401 GAAGCAGGCG GATCACTTCA GGTCAGGAGT TCGAGACCAG CCTGGCCAAC ATGGTGAAAC CCCGTCTCTA CCAAAAATAC 002480
002481 AAAAATTAGC CATGTGTAGT GGTGTGTGCC TGTAGTCCCA GCTACTTGGG AGGCTGAGGC AGGAGAATAG CTTGAGTCCC 002560
002561 GGAGGCAGAA GTTGCAGTGA GATGAGATGG CGTCACTGCA CTCCAGCCTG GGTGACAGAG CGAGACTTCA TCTCAAAAAC 002640
002641 AAAACCAAAC AAAAACAAAT TAACCAATAT ATCCCTGAAG CTACTGGTGT GTTCCTCTTC AGGCCCATTT TTGAGTAAAA 002720
002721 GTGTTTGGCT GTAAAAAGCT CAAAAGATGA GTGGCAGACG AGGGAAGCAG TGGAACTGAA TAATCTCTTA CCCAAATAAG 002800
002801 ATGAACCTAA ATGACAGATG GTTGTTTCTC CAGGTGACAG TATTAGTGGG CACCCCTAAA CTATCTTCAC ACACCCTCTG 002880
002881 CATTACTCCA CACATCCCAT TATCCCACAG CTGGTACTTC TTCACCAGGT ACTCCTGCCC CACTATCCCA CACCTAGAGG 002960
002961 ACATTTTATC CACTCAAACA GATAAATAGG CTGAAGGATT CTAATTAAGT AATAGAATCT TGCATTTTTA TAGCTCTTTA 003040
003041 CCCTTTCACA TATATCATCT CATTTGTCAC TCACCACAGT CCCCTAAGGA AAACAGCTAC TTTCTTTCAG ACAGGCAATT 003120
003121 TTCTAGCTGC CTGGGAGCTA GGAGGAGGAA AGGGCTTCAG CACAGGCACA GTCGCTCTTT CTCGCTTTTT TTTTTTTTTC 003200
003201 CTGTTACTAC CTTCCCACAT TAGATTATGC CTCCAGCCAG AA
Predicted Small Protein
| Name | MESTIT1_smProtein_1760:1984 |
| Length | 74 |
| Molecular weight | 8306.6629 |
| Aromaticity | 0.0945945945946 |
| Instability index | 65.0648648649 |
| Isoelectric point | 6.03729248047 |
| Runs | 9 |
| Runs residual | 0.0210283454186 |
| Runs probability | 0.0233272488174 |
| Amino acid sequence | MCLAPKLAFFPLLHTASLFEIDGHVWFEEKKPCGVSRRRKCVSSPQIFVEAALDILFCMA PMSANCRETDVDST |
| Secondary structure | LLLLLLLLLLLLLLLLLLEEELLLEEEEEELLLLLLLLEEEELLHHHHHHHHHHHHHHHL LLLLLLLLLLLLLL |
| PRMN | - |
| PiMo | - |
