MRAK052686

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Annotation

Name

MRAK052686

Alias

NA

Disease

Disease: nonalcoholic fatty liver disease (PMID:25623289)

Dysfunction type: NA

Description: Berberine ameliorates nonalcoholic fatty liver disease by a global modulation of hepatic mRNA and lncRNA expression profiles. MRAK052686, was found strongly correlated with the antioxidant factor Nrf2, and both genes were down-regulated by the steatotic liver. The reduced expression of MRAK052686 and Nrf2 was completely reversed by BBR treatment, suggesting a new mechanism accounting for the therapeutic effect of BBR.


Function

Function Mechanism: NA (PMID:25623289)

Biological Process: pathogenic process

Description: therapy target