Difference between revisions of "Lnc-SNAI1-1:1"
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===Function=== | ===Function=== | ||
| − | LncRNA regulates gene expression through SNAI1 dependant and independent mechanisms. Stimulates SNAI1 gene expression (in A549 cells) and like SNAI1 is required for cell migration. Stimulates Aurora-kinase A (AURKA) expression, a gene found ~6 megabases from LOC100887755 on chr20. SNAI1 does not appear to regulate AURKA and so LOC100887755 appears to regulate AURKA by a SNAI1 independent mechanism. | + | LncRNA regulates gene expression through SNAI1 dependant and independent mechanisms. |
| + | |||
| + | Stimulates SNAI1 gene expression (in A549 cells) and like SNAI1 is required for cell migration. | ||
| + | |||
| + | Stimulates Aurora-kinase A (AURKA) expression, a gene found ~6 megabases from LOC100887755 on chr20. SNAI1 does not appear to regulate AURKA and so LOC100887755 appears to regulate AURKA by a SNAI1 independent mechanism. | ||
===Expression=== | ===Expression=== | ||
| Line 42: | Line 46: | ||
==References== | ==References== | ||
| − | + | [http://www.lncrnadb.org/LOC100887755/ Annotation originally sourced from lncRNAdb.] | |
{{basic| | {{basic| | ||
| Line 58: | Line 62: | ||
sequence = <dnaseq>CCGTTCCTGCCTCCCACAGACACCTATTAAGTGCCTCCAGTTTTAGGAACTGGGTATAGATATGGCTGGGAACAAAATGGAAGAAAACAAAAACAAAAATCCCTGCCCTCATGGTGCTGACTCTCCTGTGGCAGAGACGGAGAAGATGAACAGGGATTTTATACCAGGCGTCAGAAGGGAACCAGTGCTAAAGAAAATGAAAACACCAGGCCGGGAGAGGCAGCTGGCATGCGGGCCGTGGTGGTTTTACGTGGCCGATTTGAGAGAGTGAGACCCCTGGGGTCTTGGAGCCAGGCCTGGGAAAAGCTACTTCACGTCAGGCCAGGGGCTGTAGCCCTGGCAACCTCCACTCCGCCTGGAAATCCTCCACCTCGGGGCCTCTCTTTGCCCAGACCTGGCCCAGGAGGAGCACATGGGAGCCGGGACCTTCCCAACAATCCTTGCCGTTGGCTCCACAAACCTCAGCCAGTCCTGCAACCTGGGATGCCTTTTCCACCAGGATGCCTGCTACTGTCACTGTTGTCATTAGATAATTAATGAACTATAATTAGAAATCATATCAATAAAATTTCACAGTCTAAGGCTGTTGAAATAGGAAAA</dnaseq>| | sequence = <dnaseq>CCGTTCCTGCCTCCCACAGACACCTATTAAGTGCCTCCAGTTTTAGGAACTGGGTATAGATATGGCTGGGAACAAAATGGAAGAAAACAAAAACAAAAATCCCTGCCCTCATGGTGCTGACTCTCCTGTGGCAGAGACGGAGAAGATGAACAGGGATTTTATACCAGGCGTCAGAAGGGAACCAGTGCTAAAGAAAATGAAAACACCAGGCCGGGAGAGGCAGCTGGCATGCGGGCCGTGGTGGTTTTACGTGGCCGATTTGAGAGAGTGAGACCCCTGGGGTCTTGGAGCCAGGCCTGGGAAAAGCTACTTCACGTCAGGCCAGGGGCTGTAGCCCTGGCAACCTCCACTCCGCCTGGAAATCCTCCACCTCGGGGCCTCTCTTTGCCCAGACCTGGCCCAGGAGGAGCACATGGGAGCCGGGACCTTCCCAACAATCCTTGCCGTTGGCTCCACAAACCTCAGCCAGTCCTGCAACCTGGGATGCCTTTTCCACCAGGATGCCTGCTACTGTCACTGTTGTCATTAGATAATTAATGAACTATAATTAGAAATCATATCAATAAAATTTCACAGTCTAAGGCTGTTGAAATAGGAAAA</dnaseq>| | ||
}} | }} | ||
| − | [[Category:Intergenic]] | + | [[Category:Intergenic]][[Category:Transcripts]] |
Latest revision as of 03:19, 26 August 2015
Please input one-sentence summary here.
Contents
Annotated Information
Name
LOC100887755
Characteristics
Two exon, 600 nt transcript
Around 50 kb 3’ from SNAI1 on the opposite strand.
In-vitro translation showed no sign of protein product.
Function
LncRNA regulates gene expression through SNAI1 dependant and independent mechanisms.
Stimulates SNAI1 gene expression (in A549 cells) and like SNAI1 is required for cell migration.
Stimulates Aurora-kinase A (AURKA) expression, a gene found ~6 megabases from LOC100887755 on chr20. SNAI1 does not appear to regulate AURKA and so LOC100887755 appears to regulate AURKA by a SNAI1 independent mechanism.
Expression
Expressed in A549 cells.
Conservation
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Misc
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Transcriptomic Nomeclature
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Regulation
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Allelic Information and Variation
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Evolution
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You can also add sub-section(s) at will.
Labs working on this lncRNA
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References
Annotation originally sourced from lncRNAdb.
Basic Information
| Transcript ID |
lnc-SNAI1-1:1 |
| Source |
LNCipedia2.1 |
| Same with |
, |
| Classification |
intergenic |
| Length |
600 nt |
| Genomic location |
chr20+:48657243..48658166 |
| Exon number |
, |
| Exons |
, |
| Genome context |
|
| Sequence |
000001 CCGTTCCTGC CTCCCACAGA CACCTATTAA GTGCCTCCAG TTTTAGGAAC TGGGTATAGA TATGGCTGGG AACAAAATGG 000080
000081 AAGAAAACAA AAACAAAAAT CCCTGCCCTC ATGGTGCTGA CTCTCCTGTG GCAGAGACGG AGAAGATGAA CAGGGATTTT 000160 000161 ATACCAGGCG TCAGAAGGGA ACCAGTGCTA AAGAAAATGA AAACACCAGG CCGGGAGAGG CAGCTGGCAT GCGGGCCGTG 000240 000241 GTGGTTTTAC GTGGCCGATT TGAGAGAGTG AGACCCCTGG GGTCTTGGAG CCAGGCCTGG GAAAAGCTAC TTCACGTCAG 000320 000321 GCCAGGGGCT GTAGCCCTGG CAACCTCCAC TCCGCCTGGA AATCCTCCAC CTCGGGGCCT CTCTTTGCCC AGACCTGGCC 000400 000401 CAGGAGGAGC ACATGGGAGC CGGGACCTTC CCAACAATCC TTGCCGTTGG CTCCACAAAC CTCAGCCAGT CCTGCAACCT 000480 000481 GGGATGCCTT TTCCACCAGG ATGCCTGCTA CTGTCACTGT TGTCATTAGA TAATTAATGA ACTATAATTA GAAATCATAT 000560 000561 CAATAAAATT TCACAGTCTA AGGCTGTTGA AATAGGAAAA |
