Difference between revisions of "TRIM52-AS1"

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NR_102759
 
NR_102759
 
[[File:TRIM52-AS is downregulated in RCC tissues and cell lines.jpg|right|thumb|400px|'''TRIM52-AS is downregulated in RCC tissues and cell lines''' <ref name="ref1" />.]]
 
[[File:TRIM52-AS is downregulated in RCC tissues and cell lines.jpg|right|thumb|400px|'''TRIM52-AS is downregulated in RCC tissues and cell lines''' <ref name="ref1" />.]]
===Characteristics===
 
  
 
===Function===
 
===Function===
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===Expression===
 
===Expression===
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Compared with the adjacent normal tissues, the expression of TRIM52-AS1 in the RCC tissues is significantly lower.<ref name="ref1" />
 
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{| class='wikitable' style="text-align:center"
 
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| | 5′-CTGGAGTGGCAGAAGTAAGG-3′<ref name="ref1" />
 
| | 5′-CTGGAGTGGCAGAAGTAAGG-3′<ref name="ref1" />
 
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Compared with the adjacent normal tissues, the expression of TRIM52-AS1 in the RCC tissues is significantly lower.<ref name="ref1" />
+
 
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==Labs working on this lncRNA==
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* Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
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==References==
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<references>
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<ref name="ref1">Liu, Z., et al., Downregulation of long non-coding RNA TRIM52-AS1 functions as a tumor suppressor in renal cell carcinoma. Mol Med Rep, 2016. 13(4): p. 3206-12.
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</ref>(1)
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</references>

Latest revision as of 12:04, 15 October 2017

Annotated Information

Approved Symbol

TRIM52-AS1 (TRIM52 antisense RNA 1)

Chromosome

5q35.3

RefSeq(supplied by NCBI)

NR_102759

TRIM52-AS is downregulated in RCC tissues and cell lines [1].

Function

Downregulation of TRIM52-AS1 has a negative effect on cellular proliferation in RCC (renal cell carcinoma) and inhibites the migration of RCC cells, indicating that TRIM52-AS1 act as a tumor suppressor gene in RCC .[1]

Expression

Compared with the adjacent normal tissues, the expression of TRIM52-AS1 in the RCC tissues is significantly lower.[1]

Experiment Forward primer Reverse primer
RT-qPCR 5′-AGAGCAAGGACTGTATGTGTTC-3′ 5′-CTGGAGTGGCAGAAGTAAGG-3′[1]

Labs working on this lncRNA

  • Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.

References

  1. 1.0 1.1 1.2 1.3 Liu, Z., et al., Downregulation of long non-coding RNA TRIM52-AS1 functions as a tumor suppressor in renal cell carcinoma. Mol Med Rep, 2016. 13(4): p. 3206-12.