Difference between revisions of "SKAP1-AS1"
Guangyu Wang (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== SKAP1-AS1 ===Approved Name=== SKAP1 antisense RNA 1 ===Previous Symbols=== _ ===Synonyms=== RP11-456D7.1 ===Chromosome=== 17q21...") |
Jiabao Cao (talk | contribs) |
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==Annotated Information== | ==Annotated Information== | ||
| − | === | + | ===Name=== |
| − | SKAP1-AS1 | + | SKAP1-AS1:SKAP1 antisense RNA 1 |
| − | + | ||
| − | SKAP1 antisense RNA 1 | + | RP11-456D7.1<ref name="ref1" /> |
| − | === | + | |
| − | + | ===Function=== | |
| − | === | + | According to the GO and pathway enrichment analyses, the target genes of RP11-456D7.1 are mainly enriched in the molecular function. In addition, RP11-456D7.1 also positively regulates CCL21, a high-affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and plays a key role in the inflammatory response.<ref name="ref1" /> |
| − | RP11-456D7.1 | + | ===Expression=== |
| − | === | + | The expression of RP11-456D7.1 is upregulated in the mild and severe pneumonia groups compared with controled groups.<ref name="ref1" /> |
| − | + | ===Diseases=== | |
| − | == | + | Pneumonia<ref name="ref1" /> |
| − | + | ==Labs working on this lncRNA== | |
| − | == | + | *Department of Hematology, Chinese PLA General Hospital, Beijing, China (mainland). |
| − | + | ==References== | |
| − | + | <references> | |
| − | + | <ref name="ref1"> | |
| − | + | Huang S, Feng C, Chen L, Huang Z, Zhou X, Li B, Wang LL, Chen W, Lv FQ, Li TS. | |
| − | + | Identification of Potential Key Long Non-Coding RNAs and Target Genes Associated | |
| + | with Pneumonia Using Long Non-Coding RNA Sequencing (lncRNA-Seq): A Preliminary | ||
| + | Study. Med Sci Monit. 2016 Sep 24;22:3394-3408. | ||
| + | </ref> | ||
| + | </references> | ||
Latest revision as of 14:53, 8 December 2017
Contents
Annotated Information
Name
SKAP1-AS1:SKAP1 antisense RNA 1
RP11-456D7.1[1]
Function
According to the GO and pathway enrichment analyses, the target genes of RP11-456D7.1 are mainly enriched in the molecular function. In addition, RP11-456D7.1 also positively regulates CCL21, a high-affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and plays a key role in the inflammatory response.[1]
Expression
The expression of RP11-456D7.1 is upregulated in the mild and severe pneumonia groups compared with controled groups.[1]
Diseases
Pneumonia[1]
Labs working on this lncRNA
- Department of Hematology, Chinese PLA General Hospital, Beijing, China (mainland).
References
- ↑ 1.0 1.1 1.2 1.3 Huang S, Feng C, Chen L, Huang Z, Zhou X, Li B, Wang LL, Chen W, Lv FQ, Li TS. Identification of Potential Key Long Non-Coding RNAs and Target Genes Associated with Pneumonia Using Long Non-Coding RNA Sequencing (lncRNA-Seq): A Preliminary Study. Med Sci Monit. 2016 Sep 24;22:3394-3408.
