Difference between revisions of "LINC00152"
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==Annotated Information== | ==Annotated Information== | ||
===Approved Symbol=== | ===Approved Symbol=== | ||
| − | LINC00152 | + | LINC00152:long intergenic non-protein coding RNA 152 |
| − | |||
| − | long intergenic non-protein coding RNA 152 | ||
===Previous Symbols=== | ===Previous Symbols=== | ||
C2orf59, NCRNA00152 | C2orf59, NCRNA00152 | ||
| Line 16: | Line 14: | ||
===Ensembl ID=== | ===Ensembl ID=== | ||
ENSG00000222041 | ENSG00000222041 | ||
| − | === | + | ===Function=== |
| − | + | Linc00152 knockdown could inhibit cell proliferation and colony formation, promote cell cycle arrest at G1 phase, trigger late apoptosis, reduce the epithelial to mesenchymal transition (EMT) program, and suppress cell migration and invasion. <ref name="ref1" /> | |
| + | ===Disease=== | ||
| + | * gastric cancer<ref name="ref1" /><ref name="ref2" /> | ||
| + | ===labs working on this lncRNA=== | ||
| + | * Department of Infectious Diseases ; Huashan Hospital; Shanghai Medical College; Fudan University ; Shanghai , China.<ref name="ref1" /> | ||
| + | * Department of Biochemistry and Molecular Biology, Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, 315211, China.<ref name="ref2" /> | ||
| + | ===References=== | ||
| + | <references> | ||
| + | <ref name="ref1">Zhao J, Liu Y, Zhang W, Zhou Z, Wu J, Cui P, et al. Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer[J]. Cell cycle. 2015,14(19):3112-23.</ref>(1) | ||
| + | <ref name="ref2">Pang Q, Ge J, Shao Y, Sun W, Song H, Xia T, et al. Increased expression of long intergenic non-coding RNA LINC00152 in gastric cancer and its clinical significance[J]. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014,35(6):5441-7.</ref>(2) | ||
| + | </references> | ||
===Sequence=== | ===Sequence=== | ||
>gi|169163205|ref|XR_042051.1| PREDICTED: Homo sapiens misc_RNA (C2orf59), miscRNA | >gi|169163205|ref|XR_042051.1| PREDICTED: Homo sapiens misc_RNA (C2orf59), miscRNA | ||
<dnaseq>ATGACAGACACCGAAAATCACGACTCAGCCCCCTCCAGCACCTCTACCTGTTGCCCGCCGATCACAGCCGGAATGCAGCTGAAAGATTCCCTGGGGCCTGGTTCCAACCGCCCACTGTGGACTCTGAGGCCTCTGCATTTGCGGGTGGTCTGCCTGTGATATTTTGGTCATGGGCTGGTCTGGTCGGTTTCCCATTTGTCTGGCCAGTCTCTATGTGTCTTAATCCCTTGTCCTTCATTAAAAGCAAAACTAAAGAAAA</dnaseq> | <dnaseq>ATGACAGACACCGAAAATCACGACTCAGCCCCCTCCAGCACCTCTACCTGTTGCCCGCCGATCACAGCCGGAATGCAGCTGAAAGATTCCCTGGGGCCTGGTTCCAACCGCCCACTGTGGACTCTGAGGCCTCTGCATTTGCGGGTGGTCTGCCTGTGATATTTTGGTCATGGGCTGGTCTGGTCGGTTTCCCATTTGTCTGGCCAGTCTCTATGTGTCTTAATCCCTTGTCCTTCATTAAAAGCAAAACTAAAGAAAA</dnaseq> | ||
Latest revision as of 15:04, 1 July 2016
Contents
Annotated Information
Approved Symbol
LINC00152:long intergenic non-protein coding RNA 152
Previous Symbols
C2orf59, NCRNA00152
Synonyms
MGC4677
Chromosome
2p11.2
RefSeq ID
XR_042051
OMIM ID
_
Ensembl ID
ENSG00000222041
Function
Linc00152 knockdown could inhibit cell proliferation and colony formation, promote cell cycle arrest at G1 phase, trigger late apoptosis, reduce the epithelial to mesenchymal transition (EMT) program, and suppress cell migration and invasion. [1]
Disease
labs working on this lncRNA
- Department of Infectious Diseases ; Huashan Hospital; Shanghai Medical College; Fudan University ; Shanghai , China.[1]
- Department of Biochemistry and Molecular Biology, Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, 315211, China.[2]
References
- ↑ 1.0 1.1 1.2 Zhao J, Liu Y, Zhang W, Zhou Z, Wu J, Cui P, et al. Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer[J]. Cell cycle. 2015,14(19):3112-23.
- ↑ 2.0 2.1 Pang Q, Ge J, Shao Y, Sun W, Song H, Xia T, et al. Increased expression of long intergenic non-coding RNA LINC00152 in gastric cancer and its clinical significance[J]. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014,35(6):5441-7.
Sequence
>gi|169163205|ref|XR_042051.1| PREDICTED: Homo sapiens misc_RNA (C2orf59), miscRNA
000001 ATGACAGACA CCGAAAATCA CGACTCAGCC CCCTCCAGCA CCTCTACCTG TTGCCCGCCG ATCACAGCCG GAATGCAGCT 000080
000081 GAAAGATTCC CTGGGGCCTG GTTCCAACCG CCCACTGTGG ACTCTGAGGC CTCTGCATTT GCGGGTGGTC TGCCTGTGAT 000160
000161 ATTTTGGTCA TGGGCTGGTC TGGTCGGTTT CCCATTTGTC TGGCCAGTCT CTATGTGTCT TAATCCCTTG TCCTTCATTA 000240
000241 AAAGCAAAAC TAAAGAAAA
000081 GAAAGATTCC CTGGGGCCTG GTTCCAACCG CCCACTGTGG ACTCTGAGGC CTCTGCATTT GCGGGTGGTC TGCCTGTGAT 000160
000161 ATTTTGGTCA TGGGCTGGTC TGGTCGGTTT CCCATTTGTC TGGCCAGTCT CTATGTGTCT TAATCCCTTG TCCTTCATTA 000240
000241 AAAGCAAAAC TAAAGAAAA
