Difference between revisions of "TRIM52-AS1"
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==Annotated Information== | ==Annotated Information== | ||
===Approved Symbol=== | ===Approved Symbol=== | ||
| − | TRIM52-AS1 | + | TRIM52-AS1 (TRIM52 antisense RNA 1) |
| − | |||
| − | TRIM52 antisense RNA 1 | ||
| − | |||
| − | |||
| − | |||
| − | |||
===Chromosome=== | ===Chromosome=== | ||
5q35.3 | 5q35.3 | ||
| − | |||
| − | |||
| − | |||
| − | |||
===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
NR_102759 | NR_102759 | ||
| − | === | + | [[File:TRIM52-AS is downregulated in RCC tissues and cell lines.jpg|right|thumb|400px|'''TRIM52-AS is downregulated in RCC tissues and cell lines''' <ref name="ref1" />.]] |
| − | + | ||
| + | ===Function=== | ||
| + | Downregulation of TRIM52-AS1 has a negative effect on cellular proliferation in RCC (renal cell carcinoma) and inhibites the migration of RCC cells, indicating that TRIM52-AS1 act as a tumor suppressor gene in RCC .<ref name="ref1" /> | ||
| + | |||
| + | ===Expression=== | ||
| + | Compared with the adjacent normal tissues, the expression of TRIM52-AS1 in the RCC tissues is significantly lower.<ref name="ref1" /> | ||
| + | {| class='wikitable' style="text-align:center" | ||
| + | |- | ||
| + | ! | Experiment | ||
| + | ! | Forward primer | ||
| + | ! | Reverse primer | ||
| + | |- | ||
| + | | rowspan="1"|RT-qPCR | ||
| + | | | 5′-AGAGCAAGGACTGTATGTGTTC-3′ | ||
| + | | | 5′-CTGGAGTGGCAGAAGTAAGG-3′<ref name="ref1" /> | ||
| + | |} | ||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | * Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China. | ||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1">Liu, Z., et al., Downregulation of long non-coding RNA TRIM52-AS1 functions as a tumor suppressor in renal cell carcinoma. Mol Med Rep, 2016. 13(4): p. 3206-12. | ||
| + | </ref>(1) | ||
| + | </references> | ||
Latest revision as of 12:04, 15 October 2017
Contents
Annotated Information
Approved Symbol
TRIM52-AS1 (TRIM52 antisense RNA 1)
Chromosome
5q35.3
RefSeq(supplied by NCBI)
NR_102759
TRIM52-AS is downregulated in RCC tissues and cell lines [1].
Function
Downregulation of TRIM52-AS1 has a negative effect on cellular proliferation in RCC (renal cell carcinoma) and inhibites the migration of RCC cells, indicating that TRIM52-AS1 act as a tumor suppressor gene in RCC .[1]
Expression
Compared with the adjacent normal tissues, the expression of TRIM52-AS1 in the RCC tissues is significantly lower.[1]
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| RT-qPCR | 5′-AGAGCAAGGACTGTATGTGTTC-3′ | 5′-CTGGAGTGGCAGAAGTAAGG-3′[1] |
Labs working on this lncRNA
- Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
