Difference between revisions of "DLGAP1-AS2"
(Created page with "LncRNA DLGAP1 antisense RNA 2 (DLGAP1-AS2),one kind cytoplasmic long non-coding RNA,was up-regulated in glioma and was quite correlated with poor prognosis of glioma patients....") |
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Approved name:DLGAP1 antisense RNA 2 | Approved name:DLGAP1 antisense RNA 2 | ||
| − | HGNC ID | + | HGNC ID:28146 |
Previous names:DLGAP1 antisense RNA 2 (non-protein coding) | Previous names:DLGAP1 antisense RNA 2 (non-protein coding) | ||
| Line 18: | Line 18: | ||
Please input information here. | Please input information here. | ||
===Function=== | ===Function=== | ||
| − | Depletion of DLGAP1-AS2 in glioma cells could inhibit cell proliferation and cell migration, and induce cell apoptosis, resulting in the suppression of the progression of glioma consequently. <ref name=" | + | Depletion of DLGAP1-AS2 in glioma cells could inhibit cell proliferation and cell migration, and induce cell apoptosis, resulting in the suppression of the progression of glioma consequently. <ref name="ref1" />. |
===Regulation=== | ===Regulation=== | ||
| Line 25: | Line 25: | ||
Yes Associated Protein 1 (YAP1) was the downstream target of DLGAP1-AS2 and DLGAP1-AS2 modulated glioma cell proliferation, migration and apoptosis via regulating YAP1<ref name="ref1" />. | Yes Associated Protein 1 (YAP1) was the downstream target of DLGAP1-AS2 and DLGAP1-AS2 modulated glioma cell proliferation, migration and apoptosis via regulating YAP1<ref name="ref1" />. | ||
===Diseases=== | ===Diseases=== | ||
| − | * glioma cells <ref name=" | + | * glioma cells <ref name="ref1" /> |
==Labs working on this lncRNA== | ==Labs working on this lncRNA== | ||
| Line 32: | Line 32: | ||
==References== | ==References== | ||
<references> | <references> | ||
| − | <ref name="ref1">Miao W, Li N, Gu B, Yi G, Su Z, Cheng H. LncRNA DLGAP1-AS2 modulates glioma development by up-regulating YAP1 expression. J Biochem. 2020 Apr 1;167(4):411-418. doi: 10.1093/jb/mvz108. </ref> | + | <ref name="ref1">Miao W, Li N, Gu B, Yi G, Su Z, Cheng H. LncRNA DLGAP1-AS2 modulates glioma development by up-regulating YAP1 expression. J Biochem. 2020 Apr 1;167(4):411-418. doi: 10.1093/jb/mvz108. </ref>(1) |
</references> | </references> | ||
Latest revision as of 10:44, 19 February 2021
LncRNA DLGAP1 antisense RNA 2 (DLGAP1-AS2),one kind cytoplasmic long non-coding RNA,was up-regulated in glioma and was quite correlated with poor prognosis of glioma patients.
Contents
Annotated Information
Name
Approved symbol:DLGAP1-AS2
Approved name:DLGAP1 antisense RNA 2
HGNC ID:28146
Previous names:DLGAP1 antisense RNA 2 (non-protein coding)
Alias symbols:MGC11082
RefSeq ID:NR_119377
LncBook ID:[1]
Characteristics
Please input information here.
Function
Depletion of DLGAP1-AS2 in glioma cells could inhibit cell proliferation and cell migration, and induce cell apoptosis, resulting in the suppression of the progression of glioma consequently. [1].
Regulation
LncRNA DLGAP1-AS2 modulates glioma development by up-regulating YAP1 expression[1].
Yes Associated Protein 1 (YAP1) was the downstream target of DLGAP1-AS2 and DLGAP1-AS2 modulated glioma cell proliferation, migration and apoptosis via regulating YAP1[1].
Diseases
- glioma cells [1]
Labs working on this lncRNA
- Department of Neurosurgery, Zhongda Hospital, Southeast University, 87 DingJiaQiao Road, Gulou District, Nanjing, Jiangsu 210009, China.[1].
