Difference between revisions of "LINC00319"
Line 22: | Line 22: | ||
===Expression=== | ===Expression=== | ||
LINC00319 is up-regulated in human primary lung adenocarcinoma tissues<ref name="ref1" />. | LINC00319 is up-regulated in human primary lung adenocarcinoma tissues<ref name="ref1" />. | ||
+ | |||
+ | LINC00319 contributed to lung adenocarcinoma progression by regulating miR-450b-5p/EZH2 signal pathway<ref name="ref2" />. | ||
===Regulation=== | ===Regulation=== |
Revision as of 05:31, 12 August 2019
Contents
Annotation
Name
Approved symbol: LINC00319
Approved name: long intergenic non-protein coding RNA 319
HGNC ID: HGNC:19730
Previous symbols: C21orf125; NCRNA00319
Previous names: chromosome 21 open reading frame 125; non-protein coding RNA 319
Alias symbols: PRED49; FLJ38036
RefSeq ID: NR_026960
LncBook ID: HSALNT0289323
Characteristics
Expression
LINC00319 is up-regulated in human primary lung adenocarcinoma tissues[1].
LINC00319 contributed to lung adenocarcinoma progression by regulating miR-450b-5p/EZH2 signal pathway[2].
Regulation
Function
Linc00319 promotes cell proliferation and invasion in lung cancer cells by directly binding with and downregulating the tumor suppressor miR-32.[1]
Disease
lung cancer [1]
lung adenocarcinoma carcinogenesis [2]
Evolution
Please input evolution information here.
Labs working on this lncRNA
- College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.[1]
- Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, China.[2]
References
- ↑ 1.0 1.1 1.2 1.3 Zhou B, Yuan W and Li X. Long Intergenic Noncoding RNA 319 (linc00319) Promotes Cell Proliferation and Invasion in Lung Cancer Cells by Directly Downregulating the Tumor Suppressor MiR-32[J]. Oncol Res, 2017.
- ↑ 2.0 2.1 2.2 Zhang ZW, Chen JJ, Xia SH, et al. Long intergenic non-protein coding RNA 319 aggravates lung adenocarcinoma carcinogenesis by modulating miR-450b-5p/EZH2[J]. Gene, 2018, 650: 60-67.