Difference between revisions of "LINC00319"

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===Expression===
 
===Expression===
 
LINC00319 is up-regulated in human primary lung adenocarcinoma tissues<ref name="ref1" />.
 
LINC00319 is up-regulated in human primary lung adenocarcinoma tissues<ref name="ref1" />.
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LINC00319 contributed to lung adenocarcinoma progression by regulating miR-450b-5p/EZH2 signal pathway<ref name="ref2" />.
  
 
===Regulation===
 
===Regulation===

Revision as of 05:31, 12 August 2019

Annotation

Name

Approved symbol: LINC00319

Approved name: long intergenic non-protein coding RNA 319

HGNC ID: HGNC:19730

Previous symbols: C21orf125; NCRNA00319

Previous names: chromosome 21 open reading frame 125; non-protein coding RNA 319

Alias symbols: PRED49; FLJ38036

RefSeq ID: NR_026960

LncBook ID: HSALNT0289323

Characteristics

Functional domains of 7SK RNA((Diribarne 2009))

Expression

LINC00319 is up-regulated in human primary lung adenocarcinoma tissues[1].

LINC00319 contributed to lung adenocarcinoma progression by regulating miR-450b-5p/EZH2 signal pathway[2].

Regulation

Function

Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP((Eichhorn 2018))

Linc00319 promotes cell proliferation and invasion in lung cancer cells by directly binding with and downregulating the tumor suppressor miR-32.[1]

Disease

lung cancer [1]

lung adenocarcinoma carcinogenesis [2]

Evolution

Please input evolution information here.

Labs working on this lncRNA

  • College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.[1]
  • Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, China.[2]

References

  1. 1.0 1.1 1.2 1.3 Zhou B, Yuan W and Li X. Long Intergenic Noncoding RNA 319 (linc00319) Promotes Cell Proliferation and Invasion in Lung Cancer Cells by Directly Downregulating the Tumor Suppressor MiR-32[J]. Oncol Res, 2017.
  2. 2.0 2.1 2.2 Zhang ZW, Chen JJ, Xia SH, et al. Long intergenic non-protein coding RNA 319 aggravates lung adenocarcinoma carcinogenesis by modulating miR-450b-5p/EZH2[J]. Gene, 2018, 650: 60-67.