Difference between revisions of "LINC00319"

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LncBook ID: [https://bigd.big.ac.cn/lncbook/transcript?transid=HSALNT0289323 HSALNT0289323]
 
LncBook ID: [https://bigd.big.ac.cn/lncbook/transcript?transid=HSALNT0289323 HSALNT0289323]
 
===Disease===
 
Disease: lung cancer [http://www.ncbi.nlm.nih.gov/pubmed/28800794 (PMID:28800794)]
 
 
Dysfunction type: regulation
 
 
Description: Linc00319 promotes cell proliferation and invasion in lung cancer cells by directly binding with and downregulating the tumor suppressor miR-32.
 
 
  
 
===Function===
 
===Function===
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Biological Process: pathogenic process
 
Biological Process: pathogenic process
 
Description: NA
 
  
 
===Characteristics ===
 
===Characteristics ===
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[[File:Model of hLarp7 recognition of the 7SK.png|right|thumb|Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP([https://www.ncbi.nlm.nih.gov/pubmed/29946027 (Eichhorn 2018)])]]
 
[[File:Model of hLarp7 recognition of the 7SK.png|right|thumb|Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP([https://www.ncbi.nlm.nih.gov/pubmed/29946027 (Eichhorn 2018)])]]
  
 +
Linc00319 promotes cell proliferation and invasion in lung cancer cells by directly binding with and downregulating the tumor suppressor miR-32.<ref name="ref1" />
 
===Disease===
 
===Disease===
colon adenocarcinoma <ref name="ref1" />
+
lung cancer <ref name="ref1" />
  
 
===Evolution===
 
===Evolution===

Revision as of 05:19, 12 August 2019

Annotation

Name

Approved symbol: LINC00319

Approved name: long intergenic non-protein coding RNA 319

HGNC ID: HGNC:19730

Previous symbols: C21orf125; NCRNA00319

Previous names: chromosome 21 open reading frame 125; non-protein coding RNA 319

Alias symbols: PRED49; FLJ38036

RefSeq ID: NR_026960

LncBook ID: HSALNT0289323

Function

Function Mechanism: ceRNA (PMID:28800794)

Biological Process: pathogenic process

Characteristics

Functional domains of 7SK RNA((Diribarne 2009))

Expression

Regulation

Function

Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP((Eichhorn 2018))

Linc00319 promotes cell proliferation and invasion in lung cancer cells by directly binding with and downregulating the tumor suppressor miR-32.[1]

Disease

lung cancer [1]

Evolution

Please input evolution information here.

Labs working on this lncRNA

  • College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.[1]

References

  1. 1.0 1.1 1.2 Zhou B, Yuan W and Li X. Long Intergenic Noncoding RNA 319 (linc00319) Promotes Cell Proliferation and Invasion in Lung Cancer Cells by Directly Downregulating the Tumor Suppressor MiR-32[J]. Oncol Res, 2017.