Lnc-ZCCHC13-1:1
Revision as of 10:57, 6 October 2014 by 111.204.253.116 (talk)
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Contents
Annotated Information
Transcriptomic Nomeclature
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Function
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Regulation
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Expression
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Allelic Information and Variation
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Evolution
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Labs working on this lncRNA
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References
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Basic Information
Transcript ID |
lnc-ZCCHC13-1:1 |
Source |
LNCipedia2.1 |
Same with |
, |
Classification |
intergenic |
Length |
1696 nt |
Genomic location |
chrX+:73164158..73290217 |
Exon number |
, |
Exons |
, |
Genome context |
|
Sequence |
000001 CTATGCCCTA GGGCTAGTGG AAGACTTAAG ATGGCGGCGT TTGCACGGAG TGCAATCACT GCGTCCTTAC GGGGGTTGCA 000080
000081 AGGCGTCCGA AGTATGAGTC CACTAACAAA AGTCCAGAAA CTCGCCAGTT AATAGTATTG TGTCTCTTCA AAATATCGGA 000160 000161 GAATAATTTC TTTCTCGCTG ATCGCCTAAC TTCTACTGAC GAAGCTTGGA AGTTGCAGAA GATGGAGTTC GCTCTTGTTG 000240 000241 CCCAGGCTGG AATGCAATGG CATGACCTTG GCTCACTGCA ACCTCTGCCT CCCCAGTTCA AGTGGTTCTC CTGCCTCAGC 000320 000321 CTCCCGAGTA GCTGAGATTA CAGAAACCAC AATAAAGGCT CTCGCCCACA TTCTTCCCTC ACCCTCTGCC TCCTGACTGA 000400 000401 CACTGGTGCT TTCCTGGGTG AACCCTGACG GTGTGGCATG CCTCTTCTTG TGATCTATTG TTCACTGTTG GCATATAGAA 000480 000481 ACACTACTGA TGCCTCAGAG ATGACCATGA TGGTGTTCTG GTGTCAGGAG AATAGCAATG CCTGGGAGTC CACCACCACC 000560 000561 ATAATCTCCT GTGATCCCAC GGAGCTGCAG TCAGAAGGGA GCAATGACAA GAAATAAGTG CTGAGCAGTT GTCATATGGT 000640 000641 GCTGGAAGAC ATGCTACTTT TCCCTGAGGG CGGAAGACAG CCTGATGACG GTGGTACAAT CAATGACATC TCTGTGCTGG 000720 000721 GAGTGACCTG CTTGGGGGCC CAGGCTGATC ATTTCACACA GACACCCCTG GATCCTGGAA GCCAAGTCCT GGTCTGGGTA 000800 000801 GACTGGGAGT GGAGGTTTGA CCACATGCAG CAGCATTAAA GGCAGCATCT CATCACAGCA GTTGCTGATT ATCTGTTTGA 000880 000881 GTTAAAGACA ACATCATGGG AGTTAGGGAA ATTTCGGAGT GTGATGCTGG AAAGCCCCTC TGTGAATGCA GAGAAAATAA 000960 000961 CCGCCACTGA AAAGAGTGTC AATAAAAATA TCAGAGATCA GCTGCTCAAC AAAGTATGAG AACTGAGCCT GAATGATCCT 001040 001041 GAGGCGGAGC AGGTGAGAGG CTGGGGCCTG CCAGATGATC ATGCTGGGCC CATTGGAATT GTTACCATCA AGGGTGTTGA 001120 001121 TTCCAACATG TGCTGTGGGA TCCCCATGAG CAATCTCCGT GACTTTCCAG TCATTAAGAT TAGGCACCGA GAAGAGGAAA 001200 001201 AGGAATAAAA TCAAACTGAT ATTTCTGGCT GGGAACCAGA TGCTGAAATG GATGAAGAGA AGTCATGAAA CTGAAAGAGC 001280 001281 ACTGAATCAC TCTGCTTAAG TGTGGAGCAG AGGATCACAT GGAAGCAGTG AAAAAGCTCC AGAATGTAGC CAGGCATGGT 001360 001361 GGCTACTGCC TGTAATCCCA GCACTTTGGG AGGCCGAGGC GGGCAGATCA CGAGGTCAGG AGATCGAGAC CATCCTGGCT 001440 001441 AACACGGTGA AACCCCGTCT CTACTAAAAA TATAAAAAAT TAGCTGGGCG TGTGGCGGGC GCCTGTAGTC CTAGCTACTT 001520 001521 GGGAGGCTGA GGCAGGAGAA TGGCGTGAAC CCAGGAGGTG GAACTTGCAG TGAGCTGAGA TCACGCCACT GCACTCCAGC 001600 001601 CTGGGCGACA GAGCGAGACT CTGTCTCTAA ATAAATAAAT AAATAAATAA ATAAATAAAT AAATAAATAA AAAAAAAAAA 001680 001681 AAAAAAAAAA AAAAAA |
Annotation (From lncRNAdb)
Section | Description |
---|---|
ID | Jpx |
Characteristics | Spliced (5 exons), with multiple isoforms. Located at the X-inactivation center (XIC), transcribed from an unmethylated CpG island 10 kb upstream of Xist. Transcribed in antisense orientation to Xist. (Johnston (2002)) |
Expression | Ubiquitously expressed. Up-regulated during both male and female embryonic stem cell differentiation (Tian (2010)). |
Function | Involved in the regulation of X chromosome inactivation in mammals via activation of the Xist RNA, possibly by interfering with Tsix expression (Tian (2010)). Jpx seems to act in trans, as its deletion prevents Xist up-regulation also from the Xist allele on the wild type chromosome (Tian (2010)). |
Conservation | First exon is highly conserved in mouse, human and cow (Chureau (2002)). |