NONHSAT089783

From LncRNAWiki
Revision as of 00:32, 17 October 2014 by 124.16.129.48 (talk)
Jump to: navigation, search

Please input one-sentence summary here.

Annotated Information

Name

LUST: LUCA-15-specific transcript.

Characteristics

~1.4 - 2.4 kb. Intronic, unspliced and transcribed antisense to the putative tumour suppressor gene RBM5/LUCA-15/H37, spanning introns 6 to 4 ((Rintala-Maki 2009)).

Contains SINE elements.

Expression

Originally cloned from an human bone marrow library ((Sutherland 2000)), this transcript is abundant in skeletal and cardiac muscle (as detected by Northern blot) ((Rintala-Maki 2009)).

Function

  • Transfection of Jurkat T cells with a 326 bp fragment of LUST (originally termed Je2) suppresses CD95-mediated apoptosis ((Sutherland 2000)).
  • Ectopic over-expression of LUST affects splicing of RBM5: it correlates with elevated expression of the full-length RBM5+5+6 splice variant, and with reduced expression of the truncated RBM5+5+6t isoform, which is cytotoxic ((Rintala-Maki 2009)).

Transcriptomic Nomeclature

Please input transcriptomic nomeclature information here.

Regulation

Please input regulation information here.

Allelic Information and Variation

Please input allelic information and variation information here.

Evolution

Please input evolution information here.

You can also add sub-section(s) at will.

Labs working on this lncRNA

Please input related labs here.

References

Please input cited references here.

Basic Information

Transcript ID

NONHSAT089783

Source

NONCODE4.0

Same with

,

Classification

antisense

Length

1386 nt

Genomic location

chr3-:50137036..50138421

Exon number

1

Exons

50137036..50138421

Genome context

Sequence
000001 AAATGCCGCC ACAGACTTTC ACTATGTTCT CTTCACTGTC AAATGGAGAG TTTGATATAC TAAGCTTACT CTCAATGGAC 000080
000081 ATAATAGGAA TATAACAAAC TAGAAAAAAG GGAAACATTA AGATGTTTTA GTGATTACCA GACAGGTATT CAGTAGTTAA 000160
000161 CAAAGCCCTG CCAGGTAGGT AGCCATGTTT AAAGGCAGAA CAAATTCTAT AATGAAGTCC TTGGTACTGT ACTTATTCTA 000240
000241 GTAACATCAA TTTTAATATA TACAAAGCTT TTTTTTTAAA AAAAAGTCAC TCCTTTGGAA CAAACCACTC CTTCAACCTT 000320
000321 TTTTTAAAAT TGTACAGACT TGTTCCATTT TCATGAATAT CTAGACTTGG TGAGTGAAGC AACCTGATTG GCTTCCATCC 000400
000401 AGCTGGTAGC ATCTTGCAAG TGATAAAACT CCACGAAGGC GAAACCACGG CTTACACCTA GAGACAGCAT TCAGATATAG 000480
000481 ACGGGATACT TGTGTTAGTC AGTTCCTTTA TAACAGGTGA ATCTCTCTCC CACTGCTTCA ACACTGCGTG ACAAAGCCAA 000560
000561 TTGGGAAGCA GCTTTACAAA TGTGACTTGA CTTGGGGATC TTCTTGATAC TTTGCCATGG CAAGGAACAA GCCGCCTGAA 000640
000641 CTAAATGCCA CTCCATTTGA TTCCACGCTT AAAGTAACCA TGCAACCGAC TATAGTCAAA AAAAAAAAGG AGTTTATAAA 000720
000721 TCATTACTTA CCTAAGGAAA AAAAAGTCCC TAAAACAAAG TTTAAAAAAG TTCCTCAGAT GCTAACATGG TTTTCAAAGA 000800
000801 GTCACATTCC TTAGCCATGG CAAACCTTTC ATTCTGAATT CATGTGCTTG AAGACTGGGG GAATCAGGAT GTTCTTTAGG 000880
000881 GACTGAGGTG GGAATGGGGA AGAGAACAAT AATATCAGGA ACTAAGCAAG CTCTCACCTG TTTTCCTCTT CATCAGCCTC 000960
000961 ACATCCGCAG GCTGAGGGCC TTCGAAGGAC TCCATCATTT CTCGAATCTG CACAGGGTTT TACATTATTT ACAGTTAAAG 001040
001041 CTTTTGCCAC ACACTATTCC CCATGGAATA GGAATTACAT CAACTGTTTA ATTAGCCAAG TTTTTTTTTT TTTTAAGATG 001120
001121 GGAGTCTCTG TCTCTCACTC ACTTGATTGC CCAGGCTGGA GTGCAGTGGC ATGATCTCAG CTCACTGCAA CCACCACCTC 001200
001201 CTGGGTTCAA GCAATTCTCC TGCCTCAGCC TCCCGAGTAG CTGGGATTAT AGGTGTGCAC CACCATGCGT GACTGATTTT 001280
001281 TTTTTTTTTT TGAGACGGAG TCTCGCTCTG TCACCCAGGC TGGAGTACAG TGACGTGATC TCGGCTCACT TCAACCTCCA 001360
001361 CCTCCTGGAT TCAAGCGATT CTTCTG
[back to top]

Predicted Small Protein

Name NONHSAT089783_smProtein_893:1090
Length 66
Molecular weight 7439.7248
Aromaticity 0.0615384615385
Instability index 45.0676923077
Isoelectric point 11.467956543
Runs 9
Runs residual 0.0118269230769
Runs probability 0.033710180769
Amino acid sequence MGKRTIISGTKQALTCFPLHQPHIRRLRAFEGLHHFSNLHRVLHYLQLKLLPHTIPHGIG
ITSTV
Secondary structure LLLEEEELLLLLLLLLLLLLLHHHHHHHHHHLLLHHHHHHHHHHHHHHHHLLLLLLLLLE
EEELL
PRMN -
PiMo -