Difference between revisions of "TRIM52-AS1"
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==Annotated Information== | ==Annotated Information== | ||
===Approved Symbol=== | ===Approved Symbol=== | ||
| − | TRIM52-AS1 | + | TRIM52-AS1 (TRIM52 antisense RNA 1) |
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| − | TRIM52 antisense RNA 1 | ||
| − | |||
| − | |||
| − | |||
| − | |||
===Chromosome=== | ===Chromosome=== | ||
5q35.3 | 5q35.3 | ||
| − | |||
| − | |||
| − | |||
| − | |||
===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
NR_102759 | NR_102759 | ||
| − | === | + | [[File:TRIM52-AS is downregulated in RCC tissues and cell lines.jpg|right|thumb|400px|'''TRIM52-AS is downregulated in RCC tissues and cell lines''' <ref name="ref1" />.]] |
| − | + | ===Characteristics=== | |
| + | |||
| + | ===Function=== | ||
| + | Downregulation of TRIM52-AS1 has a negative effect on cellular proliferation in RCC (renal cell carcinoma) and inhibites the migration of RCC cells, indicating that TRIM52-AS1 act as a tumor suppressor gene in RCC .<ref name="ref1" /> | ||
| + | |||
| + | ===Expression=== | ||
| + | {| class='wikitable' style="text-align:center" | ||
| + | |- | ||
| + | ! | Experiment | ||
| + | ! | Forward primer | ||
| + | ! | Reverse primer | ||
| + | |- | ||
| + | | rowspan="1"|RT-qPCR | ||
| + | | | 5′-AGAGCAAGGACTGTATGTGTTC-3′ | ||
| + | | | 5′-CTGGAGTGGCAGAAGTAAGG-3′<ref name="ref1" /> | ||
| + | |} | ||
| + | Compared with the adjacent normal tissues, the expression of TRIM52-AS1 in the RCC tissues is significantly lower.<ref name="ref1" /> | ||
Revision as of 11:56, 15 October 2017
Contents
Annotated Information
Approved Symbol
TRIM52-AS1 (TRIM52 antisense RNA 1)
Chromosome
5q35.3
RefSeq(supplied by NCBI)
NR_102759
TRIM52-AS is downregulated in RCC tissues and cell lines [1].
Characteristics
Function
Downregulation of TRIM52-AS1 has a negative effect on cellular proliferation in RCC (renal cell carcinoma) and inhibites the migration of RCC cells, indicating that TRIM52-AS1 act as a tumor suppressor gene in RCC .[1]
Expression
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| RT-qPCR | 5′-AGAGCAAGGACTGTATGTGTTC-3′ | 5′-CTGGAGTGGCAGAAGTAAGG-3′[1] |
