| Title | Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression |
|---|---|
| Description | Cervical squamous cell carcinoma (CESC) is a prototypical human cancer with well-characterized pathological stages of initiation and progression. However, high-resolution knowledge of the transcriptional programs underlying each stage of CESC is lacking, and important questions remain. We performed single-cell RNA sequencing of 76,911 individual cells from 13 samples of human cervical tissues at various stages of malignancy. |
| Organism | Homo |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA008573 |
| Release Date | 2026-07-02 |
| Submitter | Jinming Yu (sdyujinming@163.com) |
| Organization | Shandong First Medical University and Shandong Academy of Medical Sciences |
| Submission Date | 2022-03-09 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX001005-02 | CESC5-Adv2.count.tar.gz | 1 | Expression Profiling | 8.97 MB | tar | |
| OMIX001005-04 | CESC8-Adv5.count.tar.gz | 1 | Expression Profiling | 15.96 MB | tar | |
| OMIX001005-06 | CESC7-Adv4.count.tar.gz | 1 | Expression Profiling | 22.44 MB | tar | |
| OMIX001005-07 | CESC3-Early3.count.tar.gz | 1 | Expression Profiling | 30.65 MB | tar | |
| OMIX001005-08 | CESC2-Early2.count.tar.gz | 1 | Expression Profiling | 46 MB | tar | |
| OMIX001005-09 | CESC1-Early1.count.tar.gz | 1 | Expression Profiling | 28.79 MB | tar | |
| OMIX001005-20-10 | CIN2.count.tar.gz | 1 | Expression Profiling | 31.27 MB | tar | |
| OMIX001005-20-11 | CIN1.count.tar.gz | 1 | Expression Profiling | 24.6 MB | tar | |
| OMIX001005-12 | CESC6-Adv3.count.tar.gz | 1 | Expression Profiling | 42.33 MB | tar | |
| OMIX001005-13 | CESC4-Adv1.count.tar.gz | 1 | Expression Profiling | 16.98 MB | tar | |
| OMIX001005-14 | NC1.count.tar.gz | 1 | Expression Profiling | 15.37 MB | tar | |
| OMIX001005-15 | NC2.count.tar.gz | 1 | Expression Profiling | 21.68 MB | tar | |
| OMIX001005-16 | NC3.count.tar.gz | 1 | Expression Profiling | 22.04 MB | tar |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| To explore the molecular mechanisms and shared genetic characteristics of rheumatoid arthritis and cervical cancer based on multiple omics and clinical samples | Discover Oncology | 2025-05 | OMIX001005 | Secondary use |
| Dissecting the Single-Cell Diversity and Heterogeneity Underlying Cervical Precancerous Lesions and Cancer Tissues | Reproductive Sciences | 2024-10 | OMIX001005 | Secondary use |
| Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression | Science Advances | 2023-01 | OMIX001005 | Deposit |
| Single-cell atlas of cervical organoids uncovers epithelial immune heterogeneity and intercellular cross-talk during Chlamydia infection | Science Advances | 2025-10 | OMIX001005 | Deposit |