Adenosine deaminase 2 as a biomarker for head and neck cancers in saliva
| Title | Adenosine deaminase 2 as a biomarker for head and neck cancers in saliva |
|---|---|
| Description | To further increase the sensitivity of ADA2 detection, we developed an ELISA in which we used polyclonal antibodies to capture and detect ADA2. The use of ADA1 instead of HRP as a detection enzyme permits analyzing the samples with a broad ADA2 concentration. We developed a saliva sampling and storage protocol. Some publications indicated that ADA activity is different in healthy controls and patients with oral cancers, though the results are contradictory. We collected and analyzed saliva from head and neck cancer patients. Careful analysis showed that the enzyme's concentration depends on the type of cancer . This observation could be explained by the difference in the severity of the disease . |
| Organism | Homo sapiens |
| Data Type | Biomarker Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA010787 |
| Release Date | 2022-07-28 |
| Submitter | Wenwen Luo (luoww@stu.gzhmu.edu.cn) |
| Organization | Guangzhou Women and Children’s Medical Center |
| Submission Date | 2022-07-27 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX001399-01 | Head and neck cancers patients | 70 | Biomarker Data | 16.0 KB | xlsx | 0 | Controlled |