OMIX

Single-Cell RNA-seq Reveals a Developmental Hierarchy Super-Imposed Over Subclonal Evolution in the Cellular Ecosystem of Prostate Cancer

OMIX001545

1Summary
Title Single-Cell RNA-seq Reveals a Developmental Hierarchy Super-Imposed Over Subclonal Evolution in the Cellular Ecosystem of Prostate Cancer
Description To systematically explore genomic and transcriptomic intra-tumoral heterogeneity cooperate to shape the evolutionary course of prostate cancer ecosystem in primary tumor of un-treated PCa patients. A total of 14 surgically resected tissue samples were collected from patients with prostate cancer, which pathological type were prostatic acinar adenocarcinoma. No endocrine therapy was conducted on all patients before surgery. Cell capture and cDNA synthesis were carried out in 10X Genomics platform, and then transcriptome sequencing was performed in NovaSeq 6000 platform after meeting the all quality control.
Organism Homo sapiens
Data Type Other Type of Genomic Data
Data Accessibility Open-access
BioProject PRJCA004981
Release Date 2022-08-08
Submitter Weimin ci (ciwm@big.ac.cn)
Organization Beijing Institute of Genomics, Chinese Academy of Sciences
Submission Date 2022-08-07
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX001545-01 1 PCa_Single_Cell.rda 1 Other Type of Genomic Data 2.83 GB rda 0 Unavailable

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