Single-Cell RNA-seq Reveals a Developmental Hierarchy Super-Imposed Over Subclonal Evolution in the Cellular Ecosystem of Prostate Cancer
| Title | Single-Cell RNA-seq Reveals a Developmental Hierarchy Super-Imposed Over Subclonal Evolution in the Cellular Ecosystem of Prostate Cancer |
|---|---|
| Description | To systematically explore genomic and transcriptomic intra-tumoral heterogeneity cooperate to shape the evolutionary course of prostate cancer ecosystem in primary tumor of un-treated PCa patients. A total of 14 surgically resected tissue samples were collected from patients with prostate cancer, which pathological type were prostatic acinar adenocarcinoma. No endocrine therapy was conducted on all patients before surgery. Cell capture and cDNA synthesis were carried out in 10X Genomics platform, and then transcriptome sequencing was performed in NovaSeq 6000 platform after meeting the all quality control. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Open-access |
| BioProject | PRJCA004981 |
| Release Date | 2022-08-08 |
| Submitter | Weimin ci (ciwm@foxmail.com) |
| Organization | The Third Medical Center of Chinese PLA General Hospital |
| Submission Date | 2022-08-07 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX001545-01 | 1 PCa_Single_Cell.rda | 1 | Other Type of Genomic Data | 2.83 GB | rda | 0 | Unavailable |