| Title | Effects of different diets on CRC progression in mice |
|---|---|
| Description | Colorectal cancer (CRC) is the third most common cancer in the world and the incidence of colon cancer is increasing year by year. Therefore, it is of great significance to carry out active cancer prevention and treatment strategies to reduce the incidence and mortality of colorectal cancer. Whole grain intake may decrease the risk of CRC by increasing SCFA production by increasing beneficial gut microbes. Therefore, this study compared the effects of four different diets, including black rice, brown rice, white rice and control group, on the occurrence and development of colorectal cancer in mice. The results showed that black rice diet could slow down the occurrence and development of colorectal cancer by changing the composition of intestinal microbiota and regulating its metabolism. |
| Organism | Mus musculus |
| Data Type | Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA012074 |
| Release Date | 2024-05-31 |
| Submitter | Yi-Xuan Tu (tuyx@webmail.hzau.edu.cn) |
| Organization | Huazhong Agricultural University |
| Submission Date | 2022-09-23 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX001920-01 | Different_diets_Apc_metabolome | 156 | Metabolome Data by Mass Spectrometry (MS) | 4.2 MB | xlsx | |
| OMIX001920-02 | Different_diets_AOM/DSS_metabolome | 100 | Metabolome Data by Mass Spectrometry (MS) | 1.8 MB | xlsx | |
| OMIX001920-03 | Serum metabolome of CRC mice | 14 | Metabolome Data by Mass Spectrometry (MS) | 523.2 KB | txt |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Black rice diet alleviates colorectal cancer development through modulating tryptophan metabolism and activating AHR pathway | Imeta | 2024-01 | OMIX001920 | Deposit |