Pathophysiological role of genetic variants of ISL1 gene promoter in sporadic Tetralogy of Fallot
| Title | Pathophysiological role of genetic variants of ISL1 gene promoter in sporadic Tetralogy of Fallot |
|---|---|
| Description | Tetralogy of Fallot is the most common type of cyanotic congenital heart disease in newborns. ISL1 is a master transcription factor in second heart field development, whereas the role of ISL1 gene promoter variants in TOF patients has not been genetically investigated. In this study, we investigated ISL1 promoter variants in 601 subjects, including 308 TOF patients and 293 unrelated healthy controls by Sanger sequencing. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA012340 |
| Release Date | 2022-10-09 |
| Submitter | xiuyun yin (xiuyunyin921@163.com) |
| Organization | Wannan Medical College |
| Submission Date | 2022-10-08 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX002022-01 | TOF-ISL1-sequencing | 308 | Other Type of Genomic Data | 93.1 MB | zip | 0 | Unavailable |