OMIX002335

1Summary
Title Proteogenomics landscape of Acute Myeloid Leukemia
Description Acute myeloid leukemia (AML) is a malignant hematological cancer with the worst prognosis of all leukemia categories. Here, we reported a comprehensive proteogenomic analysis of 101 Chinese AML patients, including proteomic, phosphoproteomic analysis and an ex vivo drug sensitivity analysis in addition to Whole exome and transcriptome sequencing. We explored the impact of genomic alterations on proteomic and phosphoproteomic characterizations, and also uncovered the protein and phosphosite panel as prognostic indicators. Proteome-based unsupervised clustering revealed three subtypes with different molecular characterizations and clinical outcomes.
Organism Homo sapiens
Data Type Proteomic Data by Mass Spectrometry (MS)
Data Accessibility Controlled-access
BioProject PRJCA012927
Release Date 2023-08-12
Submitter Jia Li (jli@simm.ac.cn)
Organization Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Submission Date 2022-11-14
Request for this Data
2Files & Download

HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).

File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX002335-01 AMLG2 24 Proteomic Data by Mass Spectrometry (MS) 22.58 GB zip Controlled
OMIX002335-02 AMLG1 24 Proteomic Data by Mass Spectrometry (MS) 23.04 GB zip Controlled
OMIX002335-03 PHO-AML-G12 12 Proteomic Data by Mass Spectrometry (MS) 11.76 GB zip Controlled
OMIX002335-04 PHO-AML-G11 12 Proteomic Data by Mass Spectrometry (MS) 11.82 GB zip Controlled
OMIX002335-05 PHO-AML-G9 12 Proteomic Data by Mass Spectrometry (MS) 11.45 GB zip Controlled
OMIX002335-06 PHO-AML-G10 12 Proteomic Data by Mass Spectrometry (MS) 12.01 GB zip Controlled
OMIX002335-07 PHO-AML-G8 12 Proteomic Data by Mass Spectrometry (MS) 12.77 GB zip Controlled
OMIX002335-08 PHO-AML-G7 12 Proteomic Data by Mass Spectrometry (MS) 12.58 GB zip Controlled
OMIX002335-09 PHO-AML-G5 12 Proteomic Data by Mass Spectrometry (MS) 12.2 GB zip Controlled
OMIX002335-10 PHO-AML-G6 12 Proteomic Data by Mass Spectrometry (MS) 11.82 GB zip Controlled
OMIX002335-11 AMLG4 24 Proteomic Data by Mass Spectrometry (MS) 22.83 GB zip Controlled
OMIX002335-12 AMLG5 24 Proteomic Data by Mass Spectrometry (MS) 23.19 GB zip Controlled
OMIX002335-13 AMLG3 24 Proteomic Data by Mass Spectrometry (MS) 22.02 GB zip Controlled
OMIX002335-14 PHO-AML-G4 12 Proteomic Data by Mass Spectrometry (MS) 12.19 GB zip Controlled
OMIX002335-15 PHO-AML-G3 12 Proteomic Data by Mass Spectrometry (MS) 13.51 GB zip Controlled
OMIX002335-16 AMLG9 24 Proteomic Data by Mass Spectrometry (MS) 26.16 GB zip Controlled
OMIX002335-17 AMLG8 24 Proteomic Data by Mass Spectrometry (MS) 25.17 GB zip Controlled
OMIX002335-18 AMLG7 24 Proteomic Data by Mass Spectrometry (MS) 22.77 GB zip Controlled
OMIX002335-19 AMLG12 24 Proteomic Data by Mass Spectrometry (MS) 22.8 GB zip Controlled
OMIX002335-20 AMLG11 24 Proteomic Data by Mass Spectrometry (MS) 22.57 GB zip Controlled
OMIX002335-21 AMLG10 24 Proteomic Data by Mass Spectrometry (MS) 24.13 GB zip Controlled
OMIX002335-22 PHO-AML-G1 12 Proteomic Data by Mass Spectrometry (MS) 13.16 GB zip Controlled
OMIX002335-23 PHO-AML-G2 12 Proteomic Data by Mass Spectrometry (MS) 12.86 GB zip Controlled
OMIX002335-24 AMLG6 24 Proteomic Data by Mass Spectrometry (MS) 21.87 GB zip Controlled
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type

View All Released Data of OMIX