OMIX002487

1Summary
Title Single-cell sequencing of clinical samples of pancreatic cancer with liver metastases
Description 18 paired samples from 6 patients were collected from primary pancreatic cancer, portal blood, and liver metastases from each patient. Single-cell sequencing was performed after library building using the 10X V3 kit.
Organism Homo sapiens
Data Type Expression Profiling
Data Accessibility Open-access
BioProject PRJCA013605
Release Date 2025-02-27
Submitter Jinen Song (15324456297@163.com)
Organization Sichuan University
Submission Date 2022-12-01
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX002487-01 PDAC_scRNA_all_cell_meta_data 1 Expression Profiling 6.36 MB csv
OMIX002487-02 PDAC_scRNA_all_cell_count 1 Expression Profiling 209.99 MB txt
OMIX002487-03 PDAC_scRNA_immune_cell_count 1 Expression Profiling 77.51 MB txt
OMIX002487-04 PDAC_scRNA_immune_cell_meta_data 1 Expression Profiling 3.36 MB csv
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Immune checkpoint HLA-E:CD94-NKG2A mediates evasion of circulating tumor cells from NK cell surveillance Cancer Cell 2023-01 OMIX002487 Deposit
Protocol for identifying immune checkpoint on circulating tumor cells of human pancreatic ductal adenocarcinoma by single-cell RNA sequencing STAR Protocols 2023-09 OMIX002487 Deposit
Single-cell transcriptional dissection illuminates an evolution of immunosuppressive microenvironment during pancreatic ductal adenocarcinoma metastasis Signal Transduction and Targeted Therapy 2025-06 OMIX002487 Deposit
Immune checkpoints HLA-E:CD94-NKG2A and HLA-C:KIR2DL1 complementarily shield circulating tumor cells from NK-mediated immune surveillance Cell Discovery 2024-02 OMIX002487 Deposit

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