Single-cell RNA sequencing reveals radiochemotherapy-induced innate immune activation and MHC-II upregulation in cervical cancer
| Title | Single-cell RNA sequencing reveals radiochemotherapy-induced innate immune activation and MHC-II upregulation in cervical cancer |
|---|---|
| Description | Radiochemotherapy (RCT) is a powerful treatment for cervical cancer, which affects not only malignant cells but also the immune and stromal compartments of the tumor. Understanding the remodeling of the local ecosystem induced by RCT would provide valuable insights into improving treatment strategies for cervical cancer. In this study, we applied single-cell RNA sequencing to paired pre- and post-RCT tumor biopsies from patients with cervical cancer and adjacent normal cervical tissues. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA011382 |
| Release Date | 2023-02-15 |
| Submitter | Chao Liu (charles.liu@whu.edu.cn) |
| Organization | Shandong Cancer Hospital and Institute |
| Submission Date | 2022-12-02 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX002494-01 | human_Serum | 8 | Expression Profiling by NGS | 115.57 MB | zip | 0 | Unavailable |