| Title | mRNA expression profiles of BT474 cells after the treatment of pyrotinib, tamoxifen, dalpiciclib and their combination |
|---|---|
| Description | The HER2+HR+ BT474 cells were treated with DMSO(control group), pyrotinib, tamoxifen, dalpiciclib, pyrotinib+tamoxifen, pyrotinib+dalpiciclib, tamoxifen+dalpiciclib and pyrotinib+tamoxifen+dalpiciclib. The mRNA expression of BT474 cells treated with different drugs mentioned above were sequenced and uploaded. In the expression matrix we uploaded, A stands for pyrotinib treatment, B stands for tamoxifen treatment, C stands for dalpiciclib treatment, AB stands for pyrotinib+tamoxifen treatment, AC stands for pyrotinib+dalpiciclib treatment, BC stands for tamoxifen+dalpiciclib treatment and ABC stands for pyrotinib+tamoxifen+dalpiciclib treatment. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by Array |
| Data Accessibility | Open-access |
| BioProject | PRJCA013651 |
| Release Date | 2022-12-06 |
| Submitter | Caigang Liu (liucg@sj-hospital.org) |
| Organization | Shengjing Hospital of China Medical University |
| Submission Date | 2022-12-04 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX002504-01 | Expression matrix of BT474 cells treated with different durgs and their combination | 1 | Expression Profiling by Array | 65.9 MB | xls |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Dalpiciclib partially abrogates ER signaling activation induced by pyrotinib in HER2+HR+ breast cancer | eLife | 2023-01 | OMIX002504 | Deposit |