hDPSC-loaded GelMA microsphere regenerates dental pulp
| Title | hDPSC-loaded GelMA microsphere regenerates dental pulp |
|---|---|
| Description | Dental pulp regeneration is an ideal therapy for irreversible pulp lesions or periapical lesions. In situ stem cell therapy is most ideal in stem cell therapy. We provide an atlas of the conventionally extracted and monolayer cultured dental pulp stem cells (DPSCs) with single-cell RNA sequencing. Monolayer cultured dental pulp cells cluster more closely together than non-cultured dental pulp cells, suggesting a lower heterogeneous population with relatively constant clusters and similar cellular composition. We successfully layer-by-layer fabricate hDPSC-loaded microspheres on a digital light processing (DLP) printer. hDPSC-loaded microspheres have improved stemness and higher multi-directional differentiation potential, including angiogenic, neurogenic and odontogenic differentiation. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA013541 |
| Release Date | 2023-07-02 |
| Submitter | Mengfei Yu (yumengfei@zju.edu.cn) |
| Organization | Zhejiang University School of Medicine |
| Submission Date | 2022-12-31 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX002712-02 | pulp | 1 | Other Type of Genomic Data | 34.1 MB | rar | 0 | Unavailable |