Genomic and Transcriptomic Landscape of Breast Cancer with Neoadjuvant Chemotherapy
| Title | Genomic and Transcriptomic Landscape of Breast Cancer with Neoadjuvant Chemotherapy |
|---|---|
| Description | We performed whole-exome and RNA sequencing (RNAseq) analysis on the clinical samples (including matched pre- and posttreatment tumors) from 50 BC patients with rigorously definite response to NAC. This study revealed an improved understanding of genomic and transcriptomic landscape related to NAC in BC, identified novel biomarkers underlying NAC resistance and provided therapeutics opportunity beyond current neoadjuvant regimens. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA013875 |
| Release Date | 2023-12-30 |
| Submitter | Zhigang Yu (yzg@medmail.com.cn) |
| Organization | The Second Hospital of Shandong University |
| Submission Date | 2023-01-10 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX002785-01 | NACBC_WES | 91 | Other Type of Genomic Data | 5.8 MB | maf | 0 | Unavailable |
| OMIX002785-02 | NACBC_rawcount | 95 | Other Type of Genomic Data | 13.6 MB | txt | 0 | Unavailable |
| OMIX002785-03 | NACBC_gene_TPM | 95 | Other Type of Genomic Data | 53.6 MB | txt | 0 | Unavailable |