OMIX002785

1Summary
Title Genomic and Transcriptomic Landscape of Breast Cancer with Neoadjuvant Chemotherapy
Description We performed whole-exome and RNA sequencing (RNAseq) analysis on the clinical samples (including matched pre- and posttreatment tumors) from 50 BC patients with rigorously definite response to NAC. This study revealed an improved understanding of genomic and transcriptomic landscape related to NAC in BC, identified novel biomarkers underlying NAC resistance and provided therapeutics opportunity beyond current neoadjuvant regimens.
Organism Homo sapiens
Data Type Other Type of Genomic Data
Data Accessibility Controlled-access
BioProject PRJCA013875
Release Date 2023-12-30
Submitter Zhigang Yu (yzg@medmail.com.cn)
Organization The Second Hospital of Shandong University
Submission Date 2023-01-10
2Files & Download

The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.

File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX002785-01 NACBC_WES 91 Other Type of Genomic Data 5.8 MB maf Unavailable
OMIX002785-02 NACBC_rawcount 95 Other Type of Genomic Data 13.6 MB txt Unavailable
OMIX002785-03 NACBC_gene_TPM 95 Other Type of Genomic Data 53.6 MB txt Unavailable
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Genomic and transcriptomic analysis of breast cancer identifies novel signatures associated with response to neoadjuvant chemotherapy Genome Medicine 2024-01 OMIX002785 Deposit

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