A large-scale genome-wide association and meta-analysis of 7284 leprosy patients and 7738 healthy controls
| Title | A large-scale genome-wide association and meta-analysis of 7284 leprosy patients and 7738 healthy controls |
|---|---|
| Description | To date, genome-wide association studies (GWASs) have discovered 35 susceptible loci of leprosy; however, the cumulative effects of these loci can only partially explain the overall risk of leprosy, and the causal variants and genes within these loci remain unknown. Here, we performed a meta-analysis of GWASs for leprosy in two newly generated (5,007 cases and 4,579 controls) and multiple previously published (2,277 cases and 3,159 controls) datasets. Four novel and 14 previously reported risk loci were identified from these datasets. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA014655 |
| Release Date | 2023-02-01 |
| Submitter | Hong Liu (hongyue2519@hotmail.com) |
| Organization | Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Veneorology, Shandong First Medical University & Shandong Academy of Medical Sciences |
| Submission Date | 2023-02-01 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX002870-01 | meta_data.7z | 15022 | Other Type of Genomic Data | 98.8 MB | 7z | 0 | Unavailable |