OH2 oncolytic viral has a powerful antitumor effect in glioblastoma
| Title | OH2 oncolytic viral has a powerful antitumor effect in glioblastoma |
|---|---|
| Description | We performed RNA-seq on samples (U87_count and Case1_count) before and after OH2 treatment to analyze the molecular mechanism of OH2-induced tumor regression. Primary cells from 3 OH2 treatment-sensitive patients (Case2; Case10; Case11) and 3 insensitive patients (Case3; Case9; Case12) for RNA-seq. Whole exome sequencing was performed on 8 patients to infer differences in genomic alterations between OH2-sensitive and OH2-insensitive patients. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA015171 |
| Release Date | 2024-06-28 |
| Submitter | Wenbin Li (liwenbin@ccmu.edu.cn) |
| Organization | Beijing Tiantan Hospital, Capital Medical University |
| Submission Date | 2023-02-23 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX003088-01 | U87_count | 6 | Expression Profiling by NGS | 1.4 MB | txt | 0 | Controlled |
| OMIX003088-02 | Case1_count | 6 | Expression Profiling by NGS | 1.4 MB | txt | 0 | Controlled |
| OMIX003088-03 | geneID_count | 18 | Expression Profiling by NGS | 1.6 MB | xls | 0 | Controlled |
| OMIX003088-04 | somatic_filter.maf | 8 | Expression Profiling by NGS | 6.8 MB | csv | 0 | Controlled |