Crystal structures of auto-processed caspase-GSDMD complex
| Title | Crystal structures of auto-processed caspase-GSDMD complex |
|---|---|
| Description | In this dataset, we determined the three-dimensional structure of the self-activated caspase-1/4/11 and GSDMD, revealed a cleavage independently of the cleavage-site tetrapeptide sequence. This dataset contains six structures: 6KMT (P32 of caspase-11 mutant C254A); 6KMU (P22/P10 complex of caspase-11 mutant C254A); 6KMV (caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain); 6KMZ (caspase-4 P22/P10 C258A in complex with human GSDMD-C domain); 6KN0 (caspase-1 P20/P10 C285A in complex with human GSDMD-C domain); 6KN1 (P20/P12 of caspase-11 mutant C254A). |
| Organism | Homo sapiens |
| Data Type | Protein 3D Structure Data |
| Data Accessibility | Open-access |
| BioProject | PRJCA015611 |
| Release Date | 2023-03-20 |
| Submitter | Na Feng (fengna@ibp.ac.cn) |
| Organization | Institute of Biophysics, Chinese Academy of Sciences |
| Submission Date | 2023-03-17 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX003388-01 | Crystal structures of auto-processed caspase-GSDMD complex | 12 | Protein 3D Structure Data | 16.7 MB | zip | 0 |