Structure of human excitatory amino acid transporter 2 (EAAT2)
| Title | Structure of human excitatory amino acid transporter 2 (EAAT2) |
|---|---|
| Description | In this dataset, we report cryo-EM structures of human EAAT2 in an inward-facing conformation, in the presence of substrate glutamate ( PDB :7XR4) or selective inhibitor WAY-213613 ( PDB :7XR6). |
| Organism | Homo sapiens |
| Data Type | Protein 3D Structure Data |
| Data Accessibility | Open-access |
| BioProject | PRJCA015643 |
| Release Date | 2023-03-22 |
| Submitter | Yanli Dong (dongyl@ibp.ac.cn) |
| Organization | Institute of Biophysics, Chinese Academy of Sciences |
| Submission Date | 2023-03-21 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX003411-01 | Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with glutamate | 1 | Protein 3D Structure Data | 6.5 MB | zip | 0 | |
| OMIX003411-02 | Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with WAY-213613 | 1 | Protein 3D Structure Data | 59.8 MB | zip | 0 |