OMIX

Structure basis for transcription and replication of SARS-CoV-2

OMIX004087

1Summary
Title Structure basis for transcription and replication of SARS-CoV-2
Description cryo-EM structure of the replication and transcription complex of SARS-CoV-2
Organism Severe acute respiratory syndrome coronavirus 2
Data Type Protein 3D Structure Data
Data Accessibility Open-access
BioProject PRJCA016564
Release Date 2023-05-18
Submitter Yucen Huang (huangyc_14@163.com)
Organization Tsinghua University
Submission Date 2023-05-17
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX004087-01 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors 7 Protein 3D Structure Data 2.6 MB zip 0
OMIX004087-02 Architecture of a SARS-CoV-2 mini replication and transcription complex 2 Protein 3D Structure Data 679.2 KB zip 0
OMIX004087-03 Coupling of N7-methyltransferase and 3 '-5 ' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading 2 Protein 3D Structure Data 1.4 MB zip 0
OMIX004087-04 Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis 1 Protein 3D Structure Data 349.4 KB zip 0
OMIX004087-05 Structural basis for the neurotropic AAV9 and the engineered AAVPHP.eB recognition with cellular receptors 4 Protein 3D Structure Data 346.6 KB zip 0
OMIX004087-06 Structure of severe fever with thrombocytopenia syndrome virus L protein elucidates the mechanisms of viral transcription initiation 1 Protein 3D Structure Data 240.6 KB zip 0
OMIX004087-07 Structure of the RNA-dependent RNA polymerase from COVID-19 virus 2 Protein 3D Structure Data 300.5 KB zip 0
OMIX004087-08 Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization 2 Protein 3D Structure Data 229.5 KB zip 0
OMIX004087-09 Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization 4 Protein 3D Structure Data 481.7 KB zip 0

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