Metabolomics and Metagenomics Reveal the Impact of gd T Inhibition on Gut Microbiota and Metabolism in Periodontitis-Promoting OSCC
| Title | Metabolomics and Metagenomics Reveal the Impact of gd T Inhibition on Gut Microbiota and Metabolism in Periodontitis-Promoting OSCC |
|---|---|
| Description | In this study, a mouse model of OSCC with periodontitis was established in which gdT cells were inhibited by antibodies. Gut samples from mice were collected and analyzed by metabolomics. The analysis showed that targeting gdT resulted in changes in the levels of metabolites associated with intestinal cancer. |
| Organism | Mus |
| Data Type | Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA017220 |
| Release Date | 2024-02-02 |
| Submitter | jing li (2598295969@qq.com) |
| Organization | Sichuan University |
| Submission Date | 2023-06-12 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX004320-01 | Metabolomic sequencing data of mouse feces from the OSCC.P group and OSCC.P.GDT group were obtained using positive ion mode. | 9 | Metabolome Data by Mass Spectrometry (MS) | 36.03 MB | zip | 0 | |
| OMIX004320-02 | Metabolomic sequencing data of mouse feces from the OSCC.P group and OSCC.P.GDT group were obtained using negative ion mode. | 9 | Metabolome Data by Mass Spectrometry (MS) | 32.06 MB | zip | 0 |