OMIX004422

1Summary
Title Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-Cell stage
Description The optimization of culture conditions is one of the main strategies to improve the embryo develeopment competence in in vitro fertilization (IVF). Glucose is an important carbon source while also exists in the oviductal fluid in vivo, the effect of glucose in embryo development microenvironment is still unclear. Our data indicated the glucose may promote the development competence through increasing the lipid biosynthesis to overcoming the 2-Cell block. These findings were helpful for the further optimization of IVF culture media, as well as the estimation of embryo quality using metabolites in the culture media.
Organism Mus musculus
Data Type Expression Profiling
Data Accessibility Open-access
BioProject PRJCA017920
Release Date 2023-06-27
Submitter Zhigang Xue (xuezg@tongji.edu.cn)
Organization Tongji University
Submission Date 2023-06-26
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX004422-01 Glucose_Control_2Cell_counts 1 Expression Profiling 1.3 MB csv
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-cell stage Frontiers in Cell and Developmental Biology 2023-07 OMIX004422 Deposit

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