Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-Cell stage
| Title | Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-Cell stage |
|---|---|
| Description | The optimization of culture conditions is one of the main strategies to improve the embryo develeopment competence in in vitro fertilization (IVF). Glucose is an important carbon source while also exists in the oviductal fluid in vivo, the effect of glucose in embryo development microenvironment is still unclear. Our data indicated the glucose may promote the development competence through increasing the lipid biosynthesis to overcoming the 2-Cell block. These findings were helpful for the further optimization of IVF culture media, as well as the estimation of embryo quality using metabolites in the culture media. |
| Organism | Mus musculus |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Open-access |
| BioProject | PRJCA017920 |
| Release Date | 2023-06-27 |
| Submitter | Zhigang Xue (xuezg@tongji.edu.cn) |
| Organization | Tongji University |
| Submission Date | 2023-06-26 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX004422-01 | Glucose_Control_2Cell_counts | 1 | Expression Profiling by NGS | 1.3 MB | csv | 0 |