Lactobacillus metabolites of tryptophan were identified by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Title | Lactobacillus metabolites of tryptophan were identified by liquid chromatography-tandem mass spectrometry (LC-MS/MS) |
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Description | Patients with acute pancreatitis (AP) exhibit specific phenotypes of gut microbiota associated with severity. Gut microbiota and host interact primarily through metabolites, regrettably, little is known about their roles in AP biological networks. This study examines how enterobacterial metabolites modulate the innate immune system in AP aggravation. In AP, alterations in gut microbiota were detected via microbiomics, and the Lactobacillus metabolites of tryptophan were identified by liquid chromatography-tandem mass spectrometry (LC-MS/MS). By culturing Lactobacillus with tryptophan, differential metabolites were detected by LC-MS/MS. |
Organism | Bacteria |
Data Type | Metabolome Data by Mass Spectrometry (MS) |
Data Accessibility | Open-access |
BioProject | PRJCA018456 |
Release Date | 2023-07-19 |
Submitter | Qi Zhou (zhouqi94711@163.com) |
Organization | Dalian Medical University |
Submission Date | 2023-07-19 |
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File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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OMIX004547-01 | 200715-505002-2-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 111.81 MB | raw | 0 | |
OMIX004547-02 | 200828-519001-LacORIS-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 91.62 MB | raw | 0 | |
OMIX004547-03 | 200715-505001-1-P | 1 | Metabolome Data by Mass Spectrometry (MS) | 152.74 MB | raw | 0 | |
OMIX004547-04 | blank4-P | 1 | Metabolome Data by Mass Spectrometry (MS) | 128.52 MB | raw | 0 | |
OMIX004547-05 | blank6-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 162.17 MB | raw | 0 | |
OMIX004547-06 | blank1-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 144.67 MB | raw | 0 | |
OMIX004547-07 | blank3-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 99.97 MB | raw | 0 | |
OMIX004547-08 | 210902-507001-chunMRSroutangpeiyangji-P | 1 | Metabolome Data by Mass Spectrometry (MS) | 91.31 MB | raw | 0 | |
OMIX004547-09 | blank1-P | 1 | Metabolome Data by Mass Spectrometry (MS) | 160.44 MB | raw | 0 | |
OMIX004547-10 | 210902-507002-routangpeiyangjijiaseansuan-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 119.95 MB | raw | 0 | |
OMIX004547-11 | blank1-P(qunpu) | 1 | Metabolome Data by Mass Spectrometry (MS) | 124.24 MB | raw | 0 | |
OMIX004547-12 | blank2-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 169.06 MB | raw | 0 | |
OMIX004547-13 | 200715-505001-1-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 114.75 MB | raw | 0 | |
OMIX004547-14 | 200828-519001-LacORIS-P | 1 | Metabolome Data by Mass Spectrometry (MS) | 133.15 MB | raw | 0 | |
OMIX004547-15 | 200715-505002-2-P | 1 | Metabolome Data by Mass Spectrometry (MS) | 150.97 MB | raw | 0 | |
OMIX004547-16 | blank6-P | 1 | Metabolome Data by Mass Spectrometry (MS) | 124.99 MB | raw | 0 | |
OMIX004547-17 | 210902-507002-routangpeiyangjijiaseansuan-P | 1 | Metabolome Data by Mass Spectrometry (MS) | 89.07 MB | raw | 0 | |
OMIX004547-18 | 210902-507001-chunMRSroutangpeiyangji-N | 1 | Metabolome Data by Mass Spectrometry (MS) | 122.74 MB | raw | 0 |