Single-cell transcriptomic landscape deciphers novel olfactory neuroblastoma subtypes and intra-tumoral heterogeneity
Title | Single-cell transcriptomic landscape deciphers novel olfactory neuroblastoma subtypes and intra-tumoral heterogeneity |
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Description | Object: To explore the intra- and inter-tumoral heterogeneity of olfactory neuroblastoma (ONB). To discover ONB subtypes with distinctive expression features and different putative cellular origins, implying potential treatment strategies. To depict the tumor microenvironment landscape and cellular crosstalk with tumor cells. Methods: 10X genomics Single-cell RNA sequencing of 10 treatment-naive ONBs was conducted. |
Organism | Homo sapiens |
Data Type | Expression Profiling by NGS |
Data Accessibility | Open-access |
BioProject | PRJCA018683 |
Release Date | 2024-08-20 |
Submitter | Hongmeng Yu (hongmengyush@163.com) |
Organization | Eye & ENT Hospital of Fudan University |
Submission Date | 2023-08-11 |
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File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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OMIX004730-01 | ONB-scRNA-Counts.zip | 1 | Expression Profiling by NGS | 712.69 MB | zip | 0 |