Unraveling the Significance of MET Focal Amplification in Lung Cancer : Integrative NGS, FISH, and IHC Investigation
| Title | Unraveling the Significance of MET Focal Amplification in Lung Cancer : Integrative NGS, FISH, and IHC Investigation |
|---|---|
| Description | A total of 231 NSCLC cases were included for MET amplification/ overexpression determination using three methods: FISH, NGS, and IHC. A thorough comparison was performed between these methodologies. The clinical relevance of these approaches in predicting the efficacy of MET inhibitors was evaluated. Additionally, NGS data from 22,010 lung cancer cases in the LAVA database was utilized to examine the biological characteristics of different METamp subtypes. |
| Organism | Homo sapiens |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA019698 |
| Release Date | 2024-03-03 |
| Submitter | Yuchen Han (ychan@cmu.edu.cn) |
| Organization | Shanghai Chest Hospital, Shanghai Jiao Tong University |
| Submission Date | 2023-09-08 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX004873-01 | METamp Data | 231 | Other Type of Genomic Data | 256.2 KB | zip | 0 | Unavailable |