Early-life ruminal microbiome-derived indole-3-carboxaldehyde and prostaglandin D2 are effective promoters of rumen development
| Title | Early-life ruminal microbiome-derived indole-3-carboxaldehyde and prostaglandin D2 are effective promoters of rumen development |
|---|---|
| Description | Starchy corn-soybean starter-fed lambs exhibited the thickest ruminal epithelia and fiber-rich alfalfa hay-fed lambs had the thickest rumen muscle. Metabolome and metagenome data revealed that indole-3-carboxaldehyde (IAld) and prostaglandin D2 (PGD2) were the top characteristic ruminal metabolites associated with ruminal epithelial and muscular development, which depended on the enhanced ruminal microbial synthesis potential of IAld and PGD2. Moreover, microbial culture experiment first demonstrated that Bifidobacterium pseudolongum was able to convert tryptophan into IAld and Candida albicans was a key producer for PGD2. |
| Organism | Ovis aries |
| Data Type | Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA023620 |
| Release Date | 2024-02-19 |
| Submitter | Daming Sun (sundm128@163.com) |
| Organization | China Pharmaceutical University |
| Submission Date | 2024-02-18 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX005843-01 | GC-M8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 18.18 MB | CDF | 0 | |
| OMIX005843-02 | GC-MH1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 16.41 MB | CDF | 0 | |
| OMIX005843-03 | GC-MH2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 15.17 MB | CDF | 0 | |
| OMIX005843-04 | GC-MH3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 15.22 MB | CDF | 0 | |
| OMIX005843-05 | GC-MH4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 14.87 MB | CDF | 0 | |
| OMIX005843-06 | GC-MH5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 14.21 MB | CDF | 0 | |
| OMIX005843-07 | GC-MH6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 14.15 MB | CDF | 0 | |
| OMIX005843-08 | GC-MH7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 13.56 MB | CDF | 0 | |
| OMIX005843-09 | GC-MH8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 13.24 MB | CDF | 0 | |
| OMIX005843-10 | GC-M1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 19.05 MB | CDF | 0 | |
| OMIX005843-11 | GC-MC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 16.36 MB | CDF | 0 | |
| OMIX005843-12 | GC-MC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 16.02 MB | CDF | 0 | |
| OMIX005843-13 | GC-MC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.23 MB | CDF | 0 | |
| OMIX005843-14 | GC-MC4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 18.19 MB | CDF | 0 | |
| OMIX005843-15 | GC-MC5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 19.17 MB | CDF | 0 | |
| OMIX005843-16 | GC-MC6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 18.46 MB | CDF | 0 | |
| OMIX005843-17 | GC-MC7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 16.11 MB | CDF | 0 | |
| OMIX005843-18 | GC-MC8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17 MB | CDF | 0 | |
| OMIX005843-19 | GC-M2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 19.09 MB | CDF | 0 | |
| OMIX005843-20 | GC-MHC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.27 MB | CDF | 0 | |
| OMIX005843-21 | GC-MHC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 16.95 MB | CDF | 0 | |
| OMIX005843-22 | GC-MHC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.82 MB | CDF | 0 | |
| OMIX005843-23 | GC-MHC4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.33 MB | CDF | 0 | |
| OMIX005843-24 | GC-MHC5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 15.14 MB | CDF | 0 | |
| OMIX005843-25 | GC-MHC6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.09 MB | CDF | 0 | |
| OMIX005843-26 | GC-MHC7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 18.44 MB | CDF | 0 | |
| OMIX005843-27 | GC-MHC8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 18.26 MB | CDF | 0 | |
| OMIX005843-28 | GC-M3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 20.69 MB | CDF | 0 | |
| OMIX005843-29 | GC-M4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.6 MB | CDF | 0 | |
| OMIX005843-30 | GC-M5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.87 MB | CDF | 0 | |
| OMIX005843-31 | GC-M6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 16.17 MB | CDF | 0 | |
| OMIX005843-32 | GC-M7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 19.07 MB | CDF | 0 | |
| OMIX005843-33 | NEG-M1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.44 MB | mzXML | 0 | |
| OMIX005843-34 | NEG-M2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 128.69 MB | mzXML | 0 | |
| OMIX005843-35 | NEG-M3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 128.23 MB | mzXML | 0 | |
| OMIX005843-36 | NEG-M4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.47 MB | mzXML | 0 | |
| OMIX005843-37 | NEG-M5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.62 MB | mzXML | 0 | |
| OMIX005843-38 | NEG-M6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.17 MB | mzXML | 0 | |
| OMIX005843-39 | NEG-M7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.93 MB | mzXML | 0 | |
| OMIX005843-40 | NEG-MC7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 126.67 MB | mzXML | 0 | |
| OMIX005843-41 | NEG-M8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.61 MB | mzXML | 0 | |
| OMIX005843-42 | NEG-MC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 126.34 MB | mzXML | 0 | |
| OMIX005843-43 | NEG-MC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.12 MB | mzXML | 0 | |
| OMIX005843-44 | NEG-MC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.48 MB | mzXML | 0 | |
| OMIX005843-45 | NEG-MC4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 126.63 MB | mzXML | 0 | |
| OMIX005843-46 | NEG-MC5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.43 MB | mzXML | 0 | |
| OMIX005843-47 | NEG-MC6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 126.29 MB | mzXML | 0 | |
| OMIX005843-48 | NEG-MC8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127 MB | mzXML | 0 | |
| OMIX005843-49 | NEG-MH1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.77 MB | mzXML | 0 | |
| OMIX005843-50 | NEG-MH2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 129.12 MB | mzXML | 0 | |
| OMIX005843-51 | NEG-MH3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.54 MB | mzXML | 0 | |
| OMIX005843-52 | NEG-MH4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.43 MB | mzXML | 0 | |
| OMIX005843-53 | NEG-MH5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 128.35 MB | mzXML | 0 | |
| OMIX005843-54 | NEG-MH6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.64 MB | mzXML | 0 | |
| OMIX005843-55 | NEG-MH7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.99 MB | mzXML | 0 | |
| OMIX005843-56 | NEG-MH8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.51 MB | mzXML | 0 | |
| OMIX005843-57 | NEG-MHC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.28 MB | mzXML | 0 | |
| OMIX005843-58 | NEG-MHC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.67 MB | mzXML | 0 | |
| OMIX005843-59 | NEG-MHC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.8 MB | mzXML | 0 | |
| OMIX005843-60 | NEG-MHC4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.98 MB | mzXML | 0 | |
| OMIX005843-61 | NEG-MHC5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.51 MB | mzXML | 0 | |
| OMIX005843-62 | NEG-MHC6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.53 MB | mzXML | 0 | |
| OMIX005843-63 | NEG-MHC7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.86 MB | mzXML | 0 | |
| OMIX005843-64 | NEG-MHC8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 127.39 MB | mzXML | 0 | |
| OMIX005843-65 | NEG-QC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 45.55 MB | mzXML | 0 | |
| OMIX005843-66 | NEG-QC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 46.24 MB | mzXML | 0 | |
| OMIX005843-67 | NEG-QC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 46.05 MB | mzXML | 0 | |
| OMIX005843-68 | POS-M1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.03 GB | mzXML | 0 | |
| OMIX005843-69 | POS-M2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.25 GB | mzXML | 0 | |
| OMIX005843-70 | POS-M3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.24 GB | mzXML | 0 | |
| OMIX005843-71 | POS-M4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.02 GB | mzXML | 0 | |
| OMIX005843-72 | POS-M5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.02 GB | mzXML | 0 | |
| OMIX005843-73 | POS-M6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 968.24 MB | mzXML | 0 | |
| OMIX005843-74 | POS-M7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.17 GB | mzXML | 0 | |
| OMIX005843-75 | POS-M8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.04 GB | mzXML | 0 | |
| OMIX005843-76 | POS-MC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.16 GB | mzXML | 0 | |
| OMIX005843-77 | POS-MC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.17 GB | mzXML | 0 | |
| OMIX005843-78 | POS-MC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.13 GB | mzXML | 0 | |
| OMIX005843-79 | POS-MC4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.13 GB | mzXML | 0 | |
| OMIX005843-80 | POS-MC5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.15 GB | mzXML | 0 | |
| OMIX005843-81 | POS-MC6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.15 GB | mzXML | 0 | |
| OMIX005843-82 | POS-MC7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.13 GB | mzXML | 0 | |
| OMIX005843-83 | POS-MC8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.14 GB | mzXML | 0 | |
| OMIX005843-84 | POS-MH1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.14 GB | mzXML | 0 | |
| OMIX005843-85 | POS-MH2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.15 GB | mzXML | 0 | |
| OMIX005843-86 | POS-MH3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.17 GB | mzXML | 0 | |
| OMIX005843-87 | POS-MH4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.13 GB | mzXML | 0 | |
| OMIX005843-88 | POS-MH5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.06 GB | mzXML | 0 | |
| OMIX005843-89 | POS-MH6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.15 GB | mzXML | 0 | |
| OMIX005843-90 | POS-MH7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.04 GB | mzXML | 0 | |
| OMIX005843-91 | POS-MH8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.13 GB | mzXML | 0 | |
| OMIX005843-92 | POS-MHC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.07 GB | mzXML | 0 | |
| OMIX005843-93 | POS-MHC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.19 GB | mzXML | 0 | |
| OMIX005843-94 | POS-MHC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.18 GB | mzXML | 0 | |
| OMIX005843-95 | POS-MHC4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.16 GB | mzXML | 0 | |
| OMIX005843-96 | POS-MHC5 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.11 GB | mzXML | 0 | |
| OMIX005843-97 | POS-MHC6 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.17 GB | mzXML | 0 | |
| OMIX005843-98 | POS-MHC7 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.17 GB | mzXML | 0 | |
| OMIX005843-99 | POS-MHC8 | 1 | Metabolome Data by Mass Spectrometry (MS) | 1.15 GB | mzXML | 0 | |
| OMIX005843-100 | POS-QC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 105.66 MB | mzXML | 0 | |
| OMIX005843-101 | POS-QC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 104.91 MB | mzXML | 0 | |
| OMIX005843-102 | POS-QC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 103.59 MB | mzXML | 0 | |
| OMIX005843-103 | GC-QC1 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.71 MB | CDF | 0 | |
| OMIX005843-104 | GC-QC2 | 1 | Metabolome Data by Mass Spectrometry (MS) | 18.32 MB | CDF | 0 | |
| OMIX005843-105 | GC-QC3 | 1 | Metabolome Data by Mass Spectrometry (MS) | 18.11 MB | CDF | 0 | |
| OMIX005843-106 | GC-QC4 | 1 | Metabolome Data by Mass Spectrometry (MS) | 17.48 MB | CDF | 0 |