Transcriptome analysis of Lactobacillus crispatus FY121 on HPV oncogene-positive SiHa and HeLa cells
Title | Transcriptome analysis of Lactobacillus crispatus FY121 on HPV oncogene-positive SiHa and HeLa cells |
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Description | Our study focused on extracellular vesicles of Lactobacillus crispatus FY121 (LcEVs), a common probiotic in the female vagina. These vesicles were found to reduce the expression of the human papillomavirus E6 and E7 genes and suppress the malignant phenotype of cervical cancer cells. In addition, to further investigate the mechanism, we used transcriptomic analyses to explore the mechanism. |
Organism | Homo sapiens |
Data Type | Other Type of Genomic Data |
Data Accessibility | Open-access |
BioProject | PRJCA024838 |
Release Date | 2024-04-03 |
Submitter | Yong Fang (yong.fang@ems.hrbmu.edu.cn) |
Organization | Harbin Medical University |
Submission Date | 2024-04-02 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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OMIX006126-01 | Transcriptome analysis of Lactobacillus crispatus FY121 on HPV oncogene-positive SiHa and HeLa cells | 8 | Other Type of Genomic Data | 227.48 MB | zip | 0 | Unavailable |