Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution
Title | Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution |
---|---|
Description | The recurrence of cutaneous squamous cell carcinoma (cSCC) after surgery is associated with the reprogramming of the tumor microenvironment (TME), and remains a key factor affecting its outcomes. We employed single-cell RNA sequencing (scRNA-seq) to examine the dynamic changes in epithelial cells, T cells, myeloid cells, and fibroblasts cells between primary and recurrent cSCC. |
Organism | Homo sapiens |
Data Type | Expression Profiling by NGS |
Data Accessibility | Controlled-access |
BioProject | PRJCA025225 |
Release Date | 2024-04-15 |
Submitter | Mingzhu Yin (yinmingzhu2008@126.com) |
Organization | Chongqing University Three Gorges Hospital |
Submission Date | 2024-04-13 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
---|---|---|---|---|---|---|---|
OMIX006242-01 | cSCC scRNA-Seq | 9 | Expression Profiling by NGS | 181.37 MB | zip | 0 | Unavailable |