Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution
| Title | Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution |
|---|---|
| Description | The recurrence of cutaneous squamous cell carcinoma (cSCC) after surgery is associated with the reprogramming of the tumor microenvironment (TME), and remains a key factor affecting its outcomes. We employed single-cell RNA sequencing (scRNA-seq) to examine the dynamic changes in epithelial cells, T cells, myeloid cells, and fibroblasts cells between primary and recurrent cSCC. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA025225 |
| Release Date | 2024-04-15 |
| Submitter | Mingzhu Yin (yinmingzhu2008@126.com) |
| Organization | Chongqing University Three Gorges Hospital |
| Submission Date | 2024-04-13 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX006242-01 | cSCC scRNA-Seq | 9 | Expression Profiling by NGS | 181.37 MB | zip | 0 | Controlled |