| Title |
Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution |
| Description |
The recurrence of cutaneous squamous cell carcinoma (cSCC) after surgery is associated with the reprogramming of the tumor microenvironment (TME), and remains a key factor affecting its outcomes. We employed single-cell RNA sequencing (scRNA-seq) to examine the dynamic changes in epithelial cells, T cells, myeloid cells, and fibroblasts cells between primary and recurrent cSCC. |
| Organism |
Homo sapiens |
| Data Type |
Expression Profiling |
| Data Accessibility |
Controlled-access |
| BioProject |
PRJCA025225 |
| Release Date |
2024-04-15 |
| Submitter |
Mingzhu Yin (yinmingzhu2008@126.com) |
| Organization |
Chongqing University Three Gorges Hospital |
| Submission Date |
2024-04-13 |