| Title | Proteomic analysis of cardiac tissue in cardiomyocyte-specific IL27Ra knockout mice and IL27Raflox/flox mice |
|---|---|
| Description | Chromatographic Conditions: The sample was injected onto the analysis column Acclaim PepMap RSLC at a flow rate of 300 nL/min. Mobile Phase A consisted of ACN-H2O-FA , while Mobile Phase B was composed of ACN-H2O-FA . Gradient elution was carried out as follows: 0-4 min, 8-11% B; 4-36 min, 11-45% B; 36-39 min, 45-100% B; 39-45 min, 100% B. Mass Spectrometry Conditions: The experimental setup utilized the Q Exactive HF mass spectrometer with a primary MS resolution of 45,000, automatic gain control set at 3e6, and a maximum injection time of 30 ms. Mass spectra were acquired in full-scan mode within the m/z range of 350-1500, supplemented by MS/MS scans on the top 25 peaks. All MS/MS spectra employed data-dependent acquisition in positive ion mode with high-energy collision dissociation at a collision energy of 32. |
| Organism | Musculus |
| Data Type | Proteomic Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA025435 |
| Release Date | 2026-01-06 |
| Submitter | Bing Xiao (xiaobinggroup@163.com) |
| Organization | The Second Hospital of Hebei Medical University |
| Submission Date | 2024-04-19 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX006288-01 | DZLM20230778785 | 15 | Proteomic Data by Mass Spectrometry (MS) | 19.97 GB | tar |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Interleukin 27 deficiency drives dilated cardiomyopathy by ferroptosis | Clinical and Translational Medicine | 2025-03 | OMIX006288 | Deposit |