Identification of ferroptosis-related gene signature for tuberculosis diagnosis and therapy efficacy
| Title | Identification of ferroptosis-related gene signature for tuberculosis diagnosis and therapy efficacy |
|---|---|
| Description | Diagnosis of tuberculosis remains a challenge when microbiological tests are negative. Immune cell atlas of patients with active TB and healthy controls were established by single-cell transcriptome. Through integrated analysis of scRNA-seq data with microarray and bulk RNA sequencing data, a ferroptosis-related gene signature containing ACSL4, CTSB and TLR4 genes that were associated with tuberculosis disease was identified. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA026098 |
| Release Date | 2024-07-01 |
| Submitter | Bingfen Yang (yangbingfen@sina.com) |
| Organization | the Eighth Medical Center of PLA General Hospital |
| Submission Date | 2024-05-21 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX006478-01 | single cell sequencing of PBMCs of TB patients | 6 | Expression Profiling by NGS | 781.89 MB | tar.gz | 0 | Unavailable |