Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity
| Title | Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity |
|---|---|
| Description | Using a combination of single-cell multi-omics, lineage tracing and functional assays, we show that embryonic HSPCs are originated from heterogeneous hemogenic endothelial cells (HECs) during zebrafish embryogenesis. |
| Organism | Danio rerio |
| Data Type | Other Type of Genomic Data |
| Data Accessibility | Open-access |
| BioProject | PRJCA027034 |
| Release Date | 2024-08-31 |
| Submitter | HCD liulab (hcdliulab@126.com) |
| Organization | Institute of Zoology, Chinese Academy of Sciences |
| Submission Date | 2024-06-22 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX006721-01 | Zebrafish.scRNA_seq | 1 | Other Type of Genomic Data | 119.57 MB | tar | 0 | |
| OMIX006721-02 | Zebrafish.Cut&Tag_RAW | 2 | Other Type of Genomic Data | 81.1 MB | tar | 0 | |
| OMIX006721-03 | Zebrafish.STRT-seq_Barcodes_and_Cell_information | 3 | Other Type of Genomic Data | 112.92 KB | xlsx | 0 | |
| OMIX006721-04 | Zebrafish.scATAC-seq_RAW | 4 | Other Type of Genomic Data | 1.05 GB | tar | 0 | |
| OMIX006721-05 | Zebrafish.STRT-seq | 5 | Other Type of Genomic Data | 604.06 KB | txt | 0 | |
| OMIX006721-06 | Zebrafish.scRNA-seqandscATAC_RAW | 6 | Other Type of Genomic Data | 1.13 GB | tar | 0 |