Single nucleotide polymorphism-based analysis of adaptive mechanisms and population dynamics of Chinese high-altitude sheep breeds
| Title | Single nucleotide polymorphism-based analysis of adaptive mechanisms and population dynamics of Chinese high-altitude sheep breeds |
|---|---|
| Description | Following extensive periods of both artificial and natural selection, sheep have demonstrated exceptional adaptability to the extreme and harsh conditions of high-altitude environments. To elucidate the molecular mechanisms underlying high-altitude adaptation in sheep, we genotyped genome-wide single nucleotide polymorphisms (SNPs) of two sheep breeds living at high-altitudes in China and downloaded SNP array data for three Tibetan-lineage sheep breeds from the International Sheep Genomics Consortium (ISGC). Subsequently, we analyzed the population structure, gene flow, and genetic characteristics of the five high-altitude sheep breeds. These findings not only improve our understanding of the adaptation mechanisms of high-altitude sheep, but also lay a solid theoretical foundation for the future breeding of climate-resilient sheep varieties and the optimization of breeding strategies. |
| Organism | Ovis aries |
| Data Type | Other type of Microarray Data |
| Data Accessibility | Open-access |
| BioProject | PRJCA027405 |
| Release Date | 2024-09-30 |
| Submitter | ZP H (2013355246@qq.com) |
| Organization | Academy of Military Medical Sciences |
| Submission Date | 2024-09-29 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX007545-01 | 5S.bim | 145 | Other type of Microarray Data | 1.33 MB | bim | 0 | |
| OMIX007545-02 | 5S.bed | 145 | Other type of Microarray Data | 1.58 MB | bed | 0 | |
| OMIX007545-03 | 5S.fam | 145 | Other type of Microarray Data | 2.94 KB | fam | 0 |