OMIX

TCR/BCR repertoires in PLTB

OMIX007886

1Summary
Title TCR/BCR repertoires in PLTB
Description Tuberculosis (TB) is a leading cause of death worldwide from a single infectious agent. In China the most common extra-pulmonary TB (EPTB) is pleural tuberculosis (PLTB). An important clinical feature of PLTB is that the lymphocytes associated with TB will accumulate in the pleural fluid. The adaptive immune repertoires play important roles in Mycobacterium tuberculosis(Mtb) infection. In this study, 10 PLTB patients were enrolled, and their Peripheral Blood Mononuclear Cells(PBMCs) and Pleural Effusion Mononuclear Cells(PEMCs) were collected. After T cells were purified from PBMCs and PEMCs, high-throughput immunosequencing of the TCRβ chain(TRB), TCRγ chain(TRG), and B cell receptor(BCR) immunoglobulin heavy chain (IGH) were conducted on these samples.
Organism Homo sapiens
Data Type Demographic Data
Data Accessibility Controlled-access
BioProject PRJCA032297
Release Date 2024-11-14
Submitter Hao Li (lihaocau@cau.edu.cn)
Organization China Agricultural University
Submission Date 2024-11-13
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX007886-01 TCR/BCR repertoires 5 Demographic Data 107.6 KB zip 0 Controlled

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