TCR/BCR repertoires in PLTB
Title | TCR/BCR repertoires in PLTB |
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Description | Tuberculosis (TB) is a leading cause of death worldwide from a single infectious agent. In China the most common extra-pulmonary TB (EPTB) is pleural tuberculosis (PLTB). An important clinical feature of PLTB is that the lymphocytes associated with TB will accumulate in the pleural fluid. The adaptive immune repertoires play important roles in Mycobacterium tuberculosis(Mtb) infection. In this study, 10 PLTB patients were enrolled, and their Peripheral Blood Mononuclear Cells(PBMCs) and Pleural Effusion Mononuclear Cells(PEMCs) were collected. After T cells were purified from PBMCs and PEMCs, high-throughput immunosequencing of the TCRβ chain(TRB), TCRγ chain(TRG), and B cell receptor(BCR) immunoglobulin heavy chain (IGH) were conducted on these samples. |
Organism | Homo sapiens |
Data Type | Demographic Data |
Data Accessibility | Controlled-access |
BioProject | PRJCA032297 |
Release Date | 2024-11-14 |
Submitter | Hao Li (lihaocau@cau.edu.cn) |
Organization | China Agricultural University |
Submission Date | 2024-11-13 |
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File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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OMIX007886-01 | TCR/BCR repertoires | 5 | Demographic Data | 107.6 KB | zip | 0 | Controlled |