OMIX007944

1Summary

Title	Exploring the Molecular Mechanisms of Tirzepatide in Alleviating Metabolic Dysfunction-Associated Fatty Liver in Mice through Integration of Metabolomics, Lipidomics, and Proteomics
Description	To preliminarily explore the molecular mechanisms of tirzepatide on metabolic dysfunction-associated fatty liver disease (MAFLD), liquid chromatography-mass spectrometry (LC-MS) was employed for comprehensive metabolomic, lipidomic, and proteomic analyses in MAFLD mice fed a high-fat diet (HFD).
Organism	Mus musculus
Data Type	Proteomic Data by Mass Spectrometry (MS)
Data Accessibility	Open-access
BioProject	PRJCA032442
Release Date	2025-02-01
Submitter	Jinliang Liang (ljlj73094@126.com)
Organization	The Third Affiliated Hospital of Sun Yat-sen University
Submission Date	2024-11-18

2Files & Download

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File ID	File Title	Number/Samples	File Type	File Size	File Suffix	Download
OMIX007944-01	NCD_2	1	Proteomic Data by Mass Spectrometry (MS)	5.85 GB	raw	FTP HTTPs
OMIX007944-02	HFD_5	1	Proteomic Data by Mass Spectrometry (MS)	5.76 GB	raw	FTP HTTPs
OMIX007944-03	NCD_4	1	Proteomic Data by Mass Spectrometry (MS)	5.77 GB	raw	FTP HTTPs
OMIX007944-04	HFD_8	1	Proteomic Data by Mass Spectrometry (MS)	5.83 GB	raw	FTP HTTPs
OMIX007944-05	HFD_3	1	Proteomic Data by Mass Spectrometry (MS)	5.9 GB	raw	FTP HTTPs
OMIX007944-06	T_4	1	Proteomic Data by Mass Spectrometry (MS)	5.77 GB	raw	FTP HTTPs
OMIX007944-07	NCD_6	1	Proteomic Data by Mass Spectrometry (MS)	5.96 GB	raw	FTP HTTPs
OMIX007944-08	T_8	1	Proteomic Data by Mass Spectrometry (MS)	5.91 GB	raw	FTP HTTPs
OMIX007944-09	NCD_9	1	Proteomic Data by Mass Spectrometry (MS)	5.76 GB	raw	FTP HTTPs
OMIX007944-10	HFD_4	1	Proteomic Data by Mass Spectrometry (MS)	5.75 GB	raw	FTP HTTPs
OMIX007944-11	T_10	1	Proteomic Data by Mass Spectrometry (MS)	5.76 GB	raw	FTP HTTPs
OMIX007944-12	T_2	1	Proteomic Data by Mass Spectrometry (MS)	5.79 GB	raw	FTP HTTPs
OMIX007944-13	NCD_3	1	Proteomic Data by Mass Spectrometry (MS)	5.86 GB	raw	FTP HTTPs
OMIX007944-14	HFD_1	1	Proteomic Data by Mass Spectrometry (MS)	5.8 GB	raw	FTP HTTPs
OMIX007944-15	T_1	1	Proteomic Data by Mass Spectrometry (MS)	5.83 GB	raw	FTP HTTPs
OMIX007944-16	NCD_5	1	Proteomic Data by Mass Spectrometry (MS)	5.78 GB	raw	FTP HTTPs
OMIX007944-17	T_5	1	Proteomic Data by Mass Spectrometry (MS)	5.79 GB	raw	FTP HTTPs
OMIX007944-18	T_9	1	Proteomic Data by Mass Spectrometry (MS)	5.82 GB	raw	FTP HTTPs
OMIX007944-19	HFD_9	1	Proteomic Data by Mass Spectrometry (MS)	5.95 GB	raw	FTP HTTPs
OMIX007944-20	NCD_10	1	Proteomic Data by Mass Spectrometry (MS)	5.76 GB	raw	FTP HTTPs
OMIX007944-21	NCD_7	1	Proteomic Data by Mass Spectrometry (MS)	5.84 GB	raw	FTP HTTPs
OMIX007944-22	HFD_2	1	Proteomic Data by Mass Spectrometry (MS)	5.81 GB	raw	FTP HTTPs
OMIX007944-23	HFD_6	1	Proteomic Data by Mass Spectrometry (MS)	5.68 GB	raw	FTP HTTPs
OMIX007944-24	NCD_1	1	Proteomic Data by Mass Spectrometry (MS)	5.93 GB	raw	FTP HTTPs
OMIX007944-25	NCD_8	1	Proteomic Data by Mass Spectrometry (MS)	5.79 GB	raw	FTP HTTPs
OMIX007944-26	HFD_7	1	Proteomic Data by Mass Spectrometry (MS)	5.75 GB	raw	FTP HTTPs
OMIX007944-27	T_3	1	Proteomic Data by Mass Spectrometry (MS)	5.8 GB	raw	FTP HTTPs
OMIX007944-28	T_7	1	Proteomic Data by Mass Spectrometry (MS)	5.78 GB	raw	FTP HTTPs
OMIX007944-29	T_6	1	Proteomic Data by Mass Spectrometry (MS)	5.77 GB	raw	FTP HTTPs

3Relevant Publications

Paper Title	Journal Name	Publish Time	Accession	Citing Type
Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomics	Lipids in Health and Disease	2025-01	OMIX007944 OMIX007945 OMIX007946	Deposit

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