| Title | Transcriptomic data, mice, thoracic aortic tissues |
|---|---|
| Description | mRNA seq of mice thoracic aorta to investigate the mechanisms underlying how BMAL1 haploinsufficiency increases the TAAD risk and how ISX-9 and SR9009 reduced the TAAD risk. |
| Organism | Mus musculus |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA024384 |
| Release Date | 2025-06-01 |
| Submitter | Wenyu Song (songwy21@m.fudan.edu.cn) |
| Organization | Zhongshan Hospital, Fudan University |
| Submission Date | 2024-12-02 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX008070-01 | Wildtype (WT, n = 3) and global Bmal1 knockdown (BKD, n = 3) | 6 | Expression Profiling | 2.8 MB | xlsx | |
| OMIX008070-02 | BKD + Vehicle (n = 3) and BKD + ISX-9 (n = 3) | 6 | Expression Profiling | 2.9 MB | xlsx | |
| OMIX008070-03 | BKD + Vehicle (n = 3) and BKD + SR9009 (n = 3) | 6 | Expression Profiling | 2.8 MB | xlsx | |
| OMIX008070-04 | WT + Vehicle (n = 3), WT + ISX-9 (n = 3), and WT + SR9009 (n = 3) | 9 | Expression Profiling | 4.2 MB | xlsx |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| BMAL1 insufficiency increases the risk of thoracic aortic aneurysm and dissection | Cardiovascular Research | 2025-11 | OMIX008070 OMIX006064 OMIX006040 OMIX006014 | Deposit |