| Title | E3 Ubiquitin Ligase CHIP Facilitates cAMP and cGMP Signalling Cross-talk by Polyubiquitinating PDE9A |
|---|---|
| Description | Single-cell transcriptome sequencing expression matrix. Single-cell RNA Sequencing of CHIP p.T246M homozygous mutant Rattus norvegicus, CHIP p.T246M homozygous mutant Rattus norvegicus was received intraperitoneal injections of Bay 73-6691(2 mg/kg/day) for 15 consecutive days, CHIP p.T246M homozygous mutant Rattus norvegicus was intravenously injected with HBAAV2/BBB-CHIP virus (1.2 x 10^12 vg/mL), and Wild-type Rattus norvegicus. |
| Organism | Rattus norvegicus |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA033500 |
| Release Date | 2024-12-12 |
| Submitter | Changhe Shi (shichanghe@zzu.edu.cn) |
| Organization | The First Affiliated Hospital of Zhengzhou University |
| Submission Date | 2024-12-11 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX008238-01 | Single-cell sequencing expression matrix of Hom+AAV-CHIP rat | 1 | Expression Profiling | 40.43 MB | zip | |
| OMIX008238-02 | Single-cell sequencing expression matrix of Hom+Bay rat | 1 | Expression Profiling | 44.43 MB | zip | |
| OMIX008238-03 | Single-cell sequencing expression matrix of WT rat | 1 | Expression Profiling | 28.08 MB | zip | |
| OMIX008238-04 | Single-cell sequencing expression matrix of Hom rat | 1 | Expression Profiling | 34.82 MB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A | The Embo Journal | 2025-01 | OMIX008238 | Deposit |