| Title | Metabolomic and proteomic data for the treatment of Alzheimer's disease with Total Saikosaponins |
|---|---|
| Description | In the metabolomics experiment, the analytical instrument used was an LC-MS system, specifically the ACQUITY UPLC I-Class plus ultra-performance liquid chromatograph from Waters Corporation, coupled with a QE plus high-resolution mass spectrometer from Thermo Fisher Scientific. This mass spectrometer is equipped with a heated electrospray ionization (ESI) source and is used to analyze metabolic profiles in both positive and negative ESI modes. For the proteomics experiment, each fraction collected from the previous pre-separation step was loaded onto an EASY-nLC 1200 liquid chromatography system for further separation. The system was set to a flow rate of 300 nL/min. Mobile phase A was composed of ACN-H2O-FA in a 99.9:0.1 volume ratio, while mobile phase B was composed of ACN-H2O-FA in an 80:19.9:0.1 volume ratio. |
| Organism | Mus musculus |
| Data Type | Other Type of Metabolome Data |
| Data Accessibility | Open-access |
| BioProject | PRJCA034124 |
| Release Date | 2025-01-08 |
| Submitter | Yao Yao (20070007@nxmu.edu.cn) |
| Organization | Ningxia Medical University |
| Submission Date | 2025-01-08 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX008611-05 | Metabolimic and proteomics methodology | 4 | Other Type of Metabolome Data | 173.7 KB | zip | |
| OMIX008611-06 | Proteomic Data by Mass Spectrometry-2 | 1 | Other Type of Metabolome Data | 3.35 GB | zip | |
| OMIX008611-07 | Proteomic Data by Mass Spectrometry-3 | 2 | Other Type of Metabolome Data | 7.02 GB | zip | |
| OMIX008611-08 | Proteomic Data by Mass Spectrometry-1 | 1 | Other Type of Metabolome Data | 5.57 GB | tar | |
| OMIX008611-09 | Metabolome Data by Mass Spectrometry-1 | 1 | Other Type of Metabolome Data | 4.33 GB | tar | |
| OMIX008611-10 | Metabolome Data by Mass Spectrometry-2 | 1 | Other Type of Metabolome Data | 6.65 GB | tar |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Investigating the Therapeutic Mechanisms of Total Saikosaponins in Alzheimer's Disease: A Metabolomic and Proteomic Approach | Pharmaceuticals | 2025-01 | OMIX008611 | Deposit |