OMIX008637

1Summary
Title Gut microbiota alleviates immune response during E. coli-induced bladder cystitis via AhR/Prg4 activation
Description Metabolomic analysis was performed using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry following established protocols. Quality control samples were prepared by pooling equal volumes of each AH sample to assess the stability and reproducibility of the untargeted metabolic analysis. The current untargeted metabolic analysis was performed via GC-MS and LC-MS. For GC analysis, AH samples were analyzed on an Agilent 7890B gas chromatograph coupled to an Agilent 5977B MSD system, and an HP-5MS fused-silica capillary column was utilized to separate the derivatives. For LC-MS, an ACQUITY UPLC I-Class system coupled with a VION IMS QTOF Mass spectrometer was used to analyze the metabolic profiling in both ESI positive and ESI negative ion modes.
Organism Mus
Data Type Metabolome Data by Mass Spectrometry (MS)
Data Accessibility Open-access
BioProject PRJCA034856
Release Date 2025-01-13
Submitter Yang Yang (yangyilcyl@163.com)
Organization The First Affiliated Hospital of Anhui Medical University
Submission Date 2025-01-10
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX008637-01 raw data 26 Metabolome Data by Mass Spectrometry (MS) 5.14 GB tar
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Modulating the gut-bladder axis: fecal transplantation protects antibiotic-treated mice from E. coli cystitis via the Ahr/Prg4 pathway Microbiome 2025-12 OMIX008637 Deposit

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